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Clathrin, Heavy Chain (CLTC) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS439880

MBS439880 is an antibody targeting CLTC. Also known as Clathrin, Heavy Chain. Reactive in Human. Others not known.. Host: Mouse. More details

$280 / 0.02 mg (With BSA & Azide at 0.2mg/mL) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Clathrin, Heavy Chain (CLTC), Monoclonal Antibody
Full Product Name
Clathrin, Heavy Chain
Product Gene Name
Product Synonym Names
Clathrin heavy chain; Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17); CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
CLTC/1431
Host
Mouse
Species Reactivity
Human. Others not known.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Specificity
Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Molecular Weight
192kDa
3D Structure
ModBase 3D Structure for P53675
Immunogen
Purified recombinant N-terminal fragment of human Clathrin Heavy Chain
Cellular Localization
Cytoplasmic
Hu-chromosome Location
17q23.1
Positive Control
HeLa cells. Placenta or Prostate Carcinoma.
Applications Tested/Suitable for anti-CLTC antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-CLTC antibody
FC/FACS: 0.5-1ug/million cells
IF: 1-2ug/ml
WB: 0.5-1ug/ml

Product References and Citations for anti-CLTC antibody

Pearse, B.M. 1987. Clathrin and coated vesicles. EMBO J. 6: 2507-2512.

Other Notes

Small volumes of anti-CLTC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLTC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
clathrin heavy chain 2 isoform 2
NCBI Official Synonym Full Names
clathrin heavy chain like 1
NCBI Official Symbol
CLTCL1
NCBI Official Synonym Symbols
CLTD; CHC22; CLH22; CLTCL
UniProt Protein Name
Clathrin heavy chain 2
UniProt Synonym Protein Names
Clathrin heavy chain on chromosome 22; CLH-22
Protein Family
UniProt Gene Name
CLTCL1
UniProt Synonym Gene Names
CLH22; CLTCL; CLTD; CLH-22
NCBI Protein Information
clathrin heavy chain 2

NCBI Summary for CLTC

This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
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UniProt Comments for CLTC

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLTC antibody

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