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RAB5B Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS448063
3 units are in stock for immediate shipment. Please contact us for more details.

RAB5B, member RAS oncogene familyGoat polyclonal antibody to mouse Rab5b. Rab5b belongs to the small GTPase superfamily, Rab family. Rab5b is a Early Endosome Marker and functions as a key regulator of vesicular trafficking during early endocytosis. More details

$405 / 0.8 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Rab5b, Polyclonal Antibody
Full Product Name
Rab5b Polyclonal Antibody
Product Gene Name
Product Synonym Names
Anti-Rab5b; RAB5B; RAS-associated protein RAB5B; ras-related protein Rab-5B antibody
Clonality
Polyclonal
Host
Goat
Species Reactivity
Reacts against: Human, Rat, Mouse, Canine, and Monkey proteins
Form/Format
Polyclonal antibody supplied as 200ul (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Specificity
Detects Rab5b protein by Western blot in cell lysates of transfected cells with GFP-Rab5b. This Ab is specific for Rab5b, it does not recognise Rab5a and Rab5c.
Preparation and Storage
Store at -20°C for long term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Chromosome Location
Chromosome: 12; NC_000012.12 (55973913..55996683). Location: 12q13
OMIM
179514
3D Structure
ModBase 3D Structure for P61020
Immunogen
Purified recombinant peptide derived from within residues 115 aa to the C-terminus of mouse Rab5b produced in E. coli.
Applications Tested/Suitable for anti-Rab5b antibody
Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry-(Paraffin) (IHC-P), Immunohistochemistry-(Frozen) (IHC-F)
Application Notes for anti-Rab5b antibody
WB: 1:250 - 1:1,000
IF: 1:50 - 1:250

Reactivity Chart of anti-Rab5b antibody

Goat Anti-RAB5B Polyclonal Antibody – Cat# MBS448063

Testing Data of anti-Rab5b antibody

Goat Anti-RAB5B Polyclonal Antibody, Testing Data – Cat# MBS448063

Other Notes

Small volumes of anti-Rab5b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rab5b purchase

MBS448063 is an antibody targeting Rab5b. Also known as Rab5b Polyclonal Antibody. Reactive in Reacts against: Human, Rat, Mouse, Canine, and Monkey proteins. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for Rab5b. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
RAB5B
NCBI Official Synonym Full Names
RAB5B, member RAS oncogene family
NCBI Official Symbol
RAB5B
UniProt Protein Name
Ras-related protein Rab-5B
UniProt Gene Name
RAB5B
UniProt Entry Name
RAB5B_HUMAN
NCBI Protein Information
ras-related protein Rab-5B

UniProt Comments for Rab5b

Function: Protein transport. Probably involved in vesicular traffic

By similarity.

Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.

Subunit structure: Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs. Ref.8 Ref.9

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note: Enriched in stage I melanosomes. Ref.10

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Sequence caution: The sequence AAH40143.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Rab5b antibody

 Reference Product  PubMed Publications
 EEA1 antibody  >2 publications with Rab5b and EEA1
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