Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) ELISA Kit for Human

Name: Human LILRB4 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS451116
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451116

MBS451116 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) ELISA Kit target analytes in biological samples.… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4), ELISA Kit

Full Product Name

Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) ELISA Kit

Product Gene Name

LILRB4 elisa kit

Product Synonym Names

CD85k; LILR-B4; LILRB5; HM18; ILT3; LIR-5; Immunoglobulin-like transcript 3; Leukocyte immunoglobulin-like receptor 5; CD85 antigen-like family member K

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue homogenates, cell lysates and other biological fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.058ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

49,397 Da

OMIM

U91925 mRNA

3D Structure

ModBase 3D Structure for Q8NHJ6

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of LILRB4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LILRB4. It may not necessarily be applicable to this product.

NCBI GI #

618857484

NCBI GeneID

11006

NCBI Accession #

NP_001265355.2

UniProt Primary Accession #

Q8NHJ6

UniProt Secondary Accession #

O15468; O75021; Q6FGQ9; Q8N1C7; Q8NHL5; A8MVL8

UniProt Related Accession #

Q8NHJ6

GenBank Nucleotide #

NM_001278426.3

NCBI Official Full Name

leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 1

NCBI Official Synonym Full Names

leukocyte immunoglobulin like receptor B4

NCBI Official Symbol

LILRB4

NCBI Official Synonym Symbols

ILT3; LIR5; CD85K; ILT-3; LIR-5

UniProt Protein Name

Leukocyte immunoglobulin-like receptor subfamily B member 4

UniProt Synonym Protein Names

CD85 antigen-like family member K; Immunoglobulin-like transcript 3; ILT-3; Leukocyte immunoglobulin-like receptor 5; LIR-5; Monocyte inhibitory receptor HM18; CD_antigen: CD85k

Protein Family

Leukocyte immunoglobulin-like receptor subfamily

UniProt Gene Name

LILRB4

UniProt Synonym Gene Names

ILT3; LIR5; ILT-3; LIR-5

NCBI Protein Information

leukocyte immunoglobulin-like receptor subfamily B member 4

NCBI Summary for LILRB4

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for LILRB4

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Research Articles on LILRB4

1. Identification of ILT4 as a cellular receptor for CSP C4d

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LILRB4 elisa kit

Reference Product	PubMed Publications
PTPN6 elisa kit	>7 publications with LILRB4 and PTPN6
PTPN11 elisa kit	>6 publications with LILRB4 and PTPN11

Pathways associated with LILRB4 elisa kit

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram

Diseases associated with LILRB4 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>22 publications with LILRB4 and Inflammation
Hypersensitivity Antibodies	>9 publications with LILRB4 and Hypersensitivity
Disease Models, Animal Antibodies	>6 publications with LILRB4 and Disease Models, Animal
Necrosis Antibodies	>6 publications with LILRB4 and Necrosis
Death Antibodies	>4 publications with LILRB4 and Death
Lung Diseases Antibodies	>4 publications with LILRB4 and Lung Diseases
Cardiovascular Diseases Antibodies	>3 publications with LILRB4 and Cardiovascular Diseases
Respiratory Tract Diseases Antibodies	>3 publications with LILRB4 and Respiratory Tract Diseases
Pneumonia Antibodies	>2 publications with LILRB4 and Pneumonia
Respiratory Tract Infections Antibodies	>2 publications with LILRB4 and Respiratory Tract Infections

Organs/Tissues associated with LILRB4 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>95 publications with LILRB4 and Blood
Lung Antibodies	>6 publications with LILRB4 and Lung
Uterus Antibodies	>3 publications with LILRB4 and Uterus
Spleen Antibodies	>3 publications with LILRB4 and Spleen
Intestine Antibodies	>2 publications with LILRB4 and Intestine
Pancreas Antibodies	>2 publications with LILRB4 and Pancreas
Kidney Antibodies	>2 publications with LILRB4 and Kidney
Liver Antibodies	>2 publications with LILRB4 and Liver
Brain Antibodies	>2 publications with LILRB4 and Brain
Placenta Antibodies	>1 publications with LILRB4 and Placenta