Lysyl Oxidase Like Protein 4 (LOXL4) ELISA Kit for Human

Name: Human LOXL4 ELISA Kit; Lysyl Oxidase Like Protein 4; MyBioSource
Brand: MyBioSource
SKU: MBS451353
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451353

MBS451353 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Lysyl Oxidase Like Protein 4 (LOXL4) ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Lysyl Oxidase Like Protein 4 (LOXL4), ELISA Kit

Full Product Name

Human Lysyl Oxidase Like Protein 4 (LOXL4) ELISA Kit

Product Gene Name

LOXL4 elisa kit

Product Synonym Names

LOXC,Lysyl oxidase homolog 4,Lysyl oxidase-related protein C

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.053ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

84,483 Da

OMIM

AF338441 mRNA

3D Structure

ModBase 3D Structure for Q96JB6

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of LOXL4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LOXL4. It may not necessarily be applicable to this product.

NCBI GI #

67782349

NCBI GeneID

84171

NCBI Accession #

NP_115587.6

UniProt Primary Accession #

Q96JB6

UniProt Secondary Accession #

Q5W0B3; Q96DY1; Q96PC0; Q9H6T5

UniProt Related Accession #

Q96JB6

GenBank Nucleotide #

NM_032211.6

NCBI Official Full Name

lysyl oxidase homolog 4

NCBI Official Synonym Full Names

lysyl oxidase like 4

NCBI Official Symbol

LOXL4

NCBI Official Synonym Symbols

LOXC

UniProt Protein Name

Lysyl oxidase homolog 4

UniProt Synonym Protein Names

Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C

Protein Family

Lysyl oxidase

UniProt Gene Name

LOXL4

UniProt Synonym Gene Names

LOXC

NCBI Protein Information

lysyl oxidase homolog 4

NCBI Summary for LOXL4

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]

UniProt Comments for LOXL4

May modulate the formation of a collagenous extracellular matrix.

Research Articles on LOXL4

1. In hepatocellular carcinoma, low LOXL4 expression was associated with lower overall survival rates and higher cumulative recurrence rates.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LOXL4 elisa kit

Products by Pathway	Pathway Diagram
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies	Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
Canonical And Non-Canonical TGF-B Signaling Pathway antibodies	Canonical And Non-Canonical TGF-B Signaling Pathway Diagram
Collagen Formation Pathway antibodies	Collagen Formation Pathway Diagram
Crosslinking Of Collagen Fibrils Pathway antibodies	Crosslinking Of Collagen Fibrils Pathway Diagram
Elastic Fibre Formation Pathway antibodies	Elastic Fibre Formation Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Simplified Interaction Map Between LOXL4 And Oxidative Stress Pathway antibodies	Simplified Interaction Map Between LOXL4 And Oxidative Stress Pathway Diagram

Diseases associated with LOXL4 elisa kit

Disease Name	Pubmed Publications
Carcinoma Antibodies	>16 publications with LOXL4 and Carcinoma
Breast Neoplasms Antibodies	>7 publications with LOXL4 and Breast Neoplasms
Adenocarcinoma Antibodies	>6 publications with LOXL4 and Adenocarcinoma
Disease Models, Animal Antibodies	>5 publications with LOXL4 and Disease Models, Animal
Neoplasm Invasiveness Antibodies	>4 publications with LOXL4 and Neoplasm Invasiveness
Neoplasms, Experimental Antibodies	>3 publications with LOXL4 and Neoplasms, Experimental
Urinary Bladder Neoplasms Antibodies	>3 publications with LOXL4 and Urinary Bladder Neoplasms
Lung Neoplasms Antibodies	>2 publications with LOXL4 and Lung Neoplasms
Liver Diseases Antibodies	>2 publications with LOXL4 and Liver Diseases
Fibrosis Antibodies	>2 publications with LOXL4 and Fibrosis

Organs/Tissues associated with LOXL4 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>7 publications with LOXL4 and Bone
Muscle Antibodies	>5 publications with LOXL4 and Muscle
Lung Antibodies	>5 publications with LOXL4 and Lung
Mouth Antibodies	>4 publications with LOXL4 and Mouth
Connective Tissue Antibodies	>3 publications with LOXL4 and Connective Tissue
Eye Antibodies	>3 publications with LOXL4 and Eye
Embryonic Tissue Antibodies	>3 publications with LOXL4 and Embryonic Tissue
Liver Antibodies	>2 publications with LOXL4 and Liver
Pancreas Antibodies	>2 publications with LOXL4 and Pancreas
Testis Antibodies	>2 publications with LOXL4 and Testis