Glucosidase Alpha, Acid (GaA) ELISA Kit for Human

Name: Human GaA ELISA Kit; Glucosidase Alpha, Acid; MyBioSource
Brand: MyBioSource
SKU: MBS455608
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455608

MBS455608 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucosidase Alpha, Acid (GaA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$480 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Glucosidase Alpha, Acid (GaA), ELISA Kit

Full Product Name

Human Glucosidase Alpha, Acid (GaA) ELISA Kit

Product Gene Name

GaA elisa kit

Product Synonym Names

LYAG; Acid Alpha-Glucosidase; Lysosomal Alpha-Glucosidase; Pompe Disease Glycogen Storage Disease Type II; Acid Maltase; Aglucosidase Alfa

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.064ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

105,324 Da

OMIM

Y00839 mRNA

3D Structure

ModBase 3D Structure for P10253

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of GaA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GaA. It may not necessarily be applicable to this product.

NCBI GI #

119393891

NCBI GeneID

2548

NCBI Accession #

NP_000143.2

UniProt Primary Accession #

P10253

UniProt Secondary Accession #

Q09GN4; Q14351; Q16302; Q8IWE7

UniProt Related Accession #

P10253

GenBank Nucleotide #

NM_000152.4

NCBI Official Full Name

lysosomal alpha-glucosidase preproprotein

NCBI Official Synonym Full Names

glucosidase alpha, acid

NCBI Official Symbol

GAA

NCBI Official Synonym Symbols

LYAG

UniProt Protein Name

Lysosomal alpha-glucosidase

UniProt Synonym Protein Names

Acid maltase; Aglucosidase alfa

Protein Family

Lysosomal alpha-glucosidase

UniProt Gene Name

GAA

NCBI Protein Information

lysosomal alpha-glucosidase

NCBI Summary for GaA

This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

UniProt Comments for GaA

Essential for the degradation of glygogen to glucose in lysosomes.

Research Articles on GaA

1. Compared with controls, GAA gene expression levels in coronary artery disease (CAD) patients were significantly increased, suggesting that GAA may be involved in the CAD development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GaA elisa kit

Reference Product	PubMed Publications
AGA elisa kit	>34 publications with GaA and AGA
YY1 elisa kit	>2 publications with GaA and YY1
AGL elisa kit	>1 publications with GaA and AGL
HES1 elisa kit	>1 publications with GaA and HES1

Pathways associated with GaA elisa kit

Products by Pathway	Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycogen Breakdown (glycogenolysis) Pathway antibodies	Glycogen Breakdown (glycogenolysis) Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Lysosomal Glycogen Catabolism Pathway antibodies	Lysosomal Glycogen Catabolism Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with GaA elisa kit

Disease Name	Pubmed Publications
Glycogen Storage Disease Type II Antibodies	>419 publications with GaA and Glycogen Storage Disease Type II
Liver Diseases Antibodies	>71 publications with GaA and Liver Diseases
Cardiomyopathy, Hypertrophic Antibodies	>69 publications with GaA and Cardiomyopathy, Hypertrophic
Atrophy Antibodies	>49 publications with GaA and Atrophy
Kidney Diseases Antibodies	>46 publications with GaA and Kidney Diseases
Hypertrophy Antibodies	>43 publications with GaA and Hypertrophy
Liver Neoplasms Antibodies	>43 publications with GaA and Liver Neoplasms
Neoplasms, Experimental Antibodies	>20 publications with GaA and Neoplasms, Experimental
Hypertrophy, Left Ventricular Antibodies	>19 publications with GaA and Hypertrophy, Left Ventricular
Inflammation Antibodies	>16 publications with GaA and Inflammation

Organs/Tissues associated with GaA elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>422 publications with GaA and Blood
Muscle Antibodies	>398 publications with GaA and Muscle
Brain Antibodies	>175 publications with GaA and Brain
Skin Antibodies	>68 publications with GaA and Skin
Kidney Antibodies	>67 publications with GaA and Kidney
Vascular Antibodies	>58 publications with GaA and Vascular
Pancreas Antibodies	>47 publications with GaA and Pancreas
Bone Antibodies	>42 publications with GaA and Bone
Lung Antibodies	>35 publications with GaA and Lung
Eye Antibodies	>18 publications with GaA and Eye