Histatin 5 (HTN5) ELISA Kit for Human

Name: Human HTN5 ELISA Kit; Histatin 5; MyBioSource
Brand: MyBioSource
SKU: MBS045841
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS045841

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of HTN5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Histatin 5 (HTN5), ELISA Kit

Full Product Name

Human Histatin 5 ELISA Kit

Product Gene Name

HTN5 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

0.625ng/ml-20ng/ml

Sensitivity

0.1ng/ml

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

6,149 Da

OMIM

142702

3D Structure

ModBase 3D Structure for P15516

Other Notes

Small volumes of HTN5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTN5 purchase

MBS045841 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histatin 5 (HTN5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HTN5. The ELISA analytical biochemical technique of the MBS045841 kit is based on HTN5 antibody-HTN5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HTN5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HTN5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HTN5. It may not necessarily be applicable to this product.

NCBI GI #

4557653

NCBI GeneID

3347

NCBI Accession #

NP_000191.1

UniProt Primary Accession #

P15516

UniProt Secondary Accession #

Q16243; Q502Z1

UniProt Related Accession #

P15516

GenBank Nucleotide #

NM_000200.2

NCBI Official Full Name

histatin-3

NCBI Official Synonym Full Names

histatin 3

NCBI Official Symbol

HTN3

NCBI Official Synonym Symbols

HIS2; HTN2; HTN5

UniProt Protein Name

Histatin-3

UniProt Synonym Protein Names

Basic histidine-rich protein; Hst; Histidine-rich protein 3; PBCleaved into the following 26 chains:Histatin-3His3-(20-44)-peptide; His3 20/44; Alternative name(s):; His3-(1-25)-peptide; His3 1/25; Histatin-3 1/25; Histatin-6His3-(20-43)-peptide; His3 20/43; Alternative name(s):; His3-(1-24)-peptide; His3 1/24; Histatin-3 1/24; Histatin-5His3-(20-32)-peptide; His3 20/32; Alternative name(s):; His3-(1-13)-peptide; His3 1/13; Histatin-3 1/13His3-(20-31)-peptide; His3 20/31; Alternative name(s):; His3-(1-12)-peptide; His3 1/12; Histatin-3 1/12His3-(20-30)-peptide; His3 20/30; Alternative name(s):; His3-(1-11)-peptide; His3 1/11; Histatin-3 1/11His3-(24-32)-peptide; His3 24/32; Alternative name(s):; His3-(5-13)-peptide; His3 5/13; Histatin-3 5/13His3-(24-31)-peptide; His3 24/31; Alternative name(s):; His3-(5-12)-peptide; His3 5/12; Histatin-11; Histatin-3 5/12His3-(24-30)-peptide; His3 24/30; Alternative name(s):; His3-(5-11)-peptide; His3 5/11; Histatin-12; Histatin-3 5/11His3-(25-32)-peptide; His3 25/32; Alternative name(s):; His3-(6-13)-peptide; His3 6/13; Histatin-3 6/13His3-(25-30)-peptide; His3 25/30; Alternative name(s):; His3-(6-11)-peptide; His3 6/11; Histatin-3 6/11His3-(26-32)-peptide; His3 26/32; Alternative name(s):; His3-(7-13)-peptide; His3 7/13; Histatin-3 7/13His3-(26-31)-peptide; His3 26/31; Alternative name(s):; His3-(7-12)-peptide; His3 7/12; Histatin-3 7/12His3-(26-30)-peptide; His3 26/30; Alternative name(s):; His3-(7-11)-peptide; His3 7/11; Histatin-3 7/11His3-(31-51)-peptide; His3 31/51; Alternative name(s):; His3-(12-32)-peptide; His3 12/32; Histatin-3 12/32; Histatin-4His3-(31-44)-peptide; His3 31/44; Alternative name(s):; His3-(12-25)-peptide; His3 12/25; Histatin-3 12/25; Histatin-9His3-(31-43)-peptide; His3 31/43; Alternative name(s):; His3-(12-24)-peptide; His3 12/24; Histatin-3 12/24; Histatin-7His3-(32-44)-peptide; His3 32/44; Alternative name(s):; His3-(13-25)-peptide; His3 13/25; Histatin-10; Histatin-3 13/25His3-(32-43)-peptide; His3 32-43; Alternative name(s):; His3-(13-24)-peptide; His3 13/24; Histatin-3 13/24; Histatin-8His3-(33-44)-peptide; His3 33/44; Alternative name(s):; His3-(14-25)-peptide; His3 14/25; Histatin-3 14/25His3-(33-43)-peptide; His3 33/43; Alternative name(s):; His3-(14-24)-peptide; His3 14/24; Histatin-3 14/24His3-(34-44)-peptide; His3 34/44; Alternative name(s):; His3-(15-25)-peptide; His3 15/25; Histatin-3 15/25His3-(34-43)-peptide; His3 34/43; Alternative name(s):; His3-(15-24)-peptide; His3 15/24; Histatin-3 15/24His3-(45-51)-peptide; His3 45/51; Alternative name(s):; His3-(26-32)-peptide; His3 26/32; Histatin-3 26/32His3-(47-51)-peptide; His3 47/51; Alternative name(s):; His3-(28-32)-peptide; His3 28/32; Histatin-3 28/32His3-(48-51)-peptide; His3 48/51; Alternative name(s):; His3-(29-32)-peptide; His3 29/32; Histatin-3 29/32

UniProt Gene Name

HTN3

UniProt Synonym Gene Names

HIS2; Hst; His3 20/44; His3 1/25; His3 20/43; His3 1/24; His3 20/32; His3 1/13; His3 20/31; His3 1/12; His3 20/30; His3 1/11; His3 24/32; His3 5/13; His3 24/31; His3 5/12; His3 24/30; His3 5/11; His3 25/32; His3 6/13; His3 25/30; His3 6/11; His3 26/32; Hi

UniProt Entry Name

HIS3_HUMAN

NCBI Protein Information

histatin-3; PB; hst; histatin 5; histidine-rich protein 3; basic histidine-rich protein

NCBI Summary for HTN5

This gene encodes a member of the histatin family of small, histidine-rich salivary proteins. Histatins exhibit non-immunological, anti-microbial activity in the oral cavity. [provided by RefSeq, May 2009]

UniProt Comments for HTN5

HTN3: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. Belongs to the histatin/statherin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q13

Cellular Component: extracellular region

Molecular Function: protein binding; metal ion binding

Biological Process: biomineral formation; killing of cells of another organism; defense response to bacterium; defense response to fungus

Research Articles on HTN5

1. analysis of histatin 5 uptake by Candida albicans utilizes polyamine transporters Dur3 and Dur31 proteins

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HTN5 elisa kit

Reference Product	PubMed Publications
MUC7 elisa kit	>7 publications with HTN5 and MUC7

Pathways associated with HTN5 elisa kit

Products by Pathway	Pathway Diagram
Salivary Secretion Pathway antibodies	Salivary Secretion Pathway Diagram
Salivary Secretion Pathway antibodies	Salivary Secretion Pathway Diagram

Diseases associated with HTN5 elisa kit

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>5 publications with HTN5 and Immune System Diseases
Hemolysis Antibodies	>4 publications with HTN5 and Hemolysis
Necrosis Antibodies	>4 publications with HTN5 and Necrosis
Bone Diseases Antibodies	>2 publications with HTN5 and Bone Diseases
Ventricular Dysfunction Antibodies	>1 publications with HTN5 and Ventricular Dysfunction
Cardiovascular Diseases Antibodies	>1 publications with HTN5 and Cardiovascular Diseases

Organs/Tissues associated with HTN5 elisa kit

Organ/Tissue Name	Pubmed Publications
Salivary Gland Antibodies	>18 publications with HTN5 and Salivary Gland
Uncharacterized Tissue Antibodies	>2 publications with HTN5 and Uncharacterized Tissue
Vascular Antibodies	>2 publications with HTN5 and Vascular
Connective Tissue Antibodies	>1 publications with HTN5 and Connective Tissue