Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) ELISA Kit for Mouse

Name: Mouse CX3CL1 ELISA Kit; Chemokine C-X3-C-Motif Ligand 1; MyBioSource
Brand: MyBioSource
SKU: MBS458695
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458695

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CX3CL1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to CX3CL1.… More details

$405 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Chemokine C-X3-C-Motif Ligand 1 (CX3CL1), ELISA Kit

Full Product Name

Mouse Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) ELISA Kit

Product Gene Name

CX3CL1 elisa kit

Product Synonym Names

NTN; ABCD3; C3Xkine; CXC3; CXC3C; NTT; SCYD1; ABCD3; FKN; Neurotactin; Fractalkine; Small Inducible Cytokine Subfamily D(Cys-X3-Cys)Member 1

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates or Other Biological Fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.060ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

42,099 Da

3D Structure

ModBase 3D Structure for O35188

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of CX3CL1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CX3CL1 purchase

MBS458695 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CX3CL1. The ELISA analytical biochemical technique of the MBS458695 kit is based on CX3CL1 antibody-CX3CL1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CX3CL1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CX3CL1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.

NCBI GI #

31982017

NCBI GeneID

20312

NCBI Accession #

NP_033168.2

UniProt Primary Accession #

O35188

UniProt Secondary Accession #

O35933; Q91V44

UniProt Related Accession #

O35188

GenBank Nucleotide #

NM_009142.3

NCBI Official Full Name

fractalkine

NCBI Official Synonym Full Names

chemokine (C-X3-C motif) ligand 1

NCBI Official Symbol

Cx3cl1

NCBI Official Synonym Symbols

CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e

UniProt Protein Name

Fractalkine

UniProt Synonym Protein Names

C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1

Protein Family

Fractalkine

UniProt Gene Name

Cx3cl1

UniProt Synonym Gene Names

Cx3c; Fkn; Scyd1

NCBI Protein Information

fractalkine

UniProt Comments for CX3CL1

Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (). The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).

Research Articles on CX3CL1

1. that CX3CL1-CX3CR1 signaling is a molecular mechanism capable of modulating microglial-mediated degeneration

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CX3CL1 elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram

Diseases associated with CX3CL1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>332 publications with CX3CL1 and Inflammation
Necrosis Antibodies	>177 publications with CX3CL1 and Necrosis
Cardiovascular Diseases Antibodies	>143 publications with CX3CL1 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>142 publications with CX3CL1 and Disease Models, Animal
Brain Diseases Antibodies	>98 publications with CX3CL1 and Brain Diseases
Atherosclerosis Antibodies	>86 publications with CX3CL1 and Atherosclerosis
Pain Antibodies	>58 publications with CX3CL1 and Pain
Kidney Diseases Antibodies	>55 publications with CX3CL1 and Kidney Diseases
Liver Diseases Antibodies	>47 publications with CX3CL1 and Liver Diseases
Heart Diseases Antibodies	>45 publications with CX3CL1 and Heart Diseases

Organs/Tissues associated with CX3CL1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>438 publications with CX3CL1 and Blood
Brain Antibodies	>184 publications with CX3CL1 and Brain
Kidney Antibodies	>84 publications with CX3CL1 and Kidney
Lung Antibodies	>81 publications with CX3CL1 and Lung
Liver Antibodies	>61 publications with CX3CL1 and Liver
Bone Marrow Antibodies	>43 publications with CX3CL1 and Bone Marrow
Skin Antibodies	>41 publications with CX3CL1 and Skin
Spinal Cord Antibodies	>41 publications with CX3CL1 and Spinal Cord
Intestine Antibodies	>33 publications with CX3CL1 and Intestine
Eye Antibodies	>27 publications with CX3CL1 and Eye