Histamine Receptor H1 (HRH1) ELISA Kit for Human

Name: Human HRH1 ELISA Kit; Histamine Receptor H1; MyBioSource
Brand: MyBioSource
SKU: MBS459914
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459914

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to HRH1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to HRH1.… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Histamine Receptor H1 (HRH1), ELISA Kit

Full Product Name

Human Histamine Receptor H1 (HRH1) ELISA Kit

Product Gene Name

HRH1 elisa kit

Product Synonym Names

H1-R; hisH1

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.128ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

55,784 Da

OMIM

600167

3D Structure

ModBase 3D Structure for P35367

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of HRH1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HRH1 purchase

MBS459914 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histamine Receptor H1 (HRH1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HRH1. The ELISA analytical biochemical technique of the MBS459914 kit is based on HRH1 antibody-HRH1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HRH1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HRH1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HRH1. It may not necessarily be applicable to this product.

NCBI GI #

4504491

NCBI GeneID

3269

NCBI Accession #

NP_000852.1

UniProt Primary Accession #

P35367

UniProt Secondary Accession #

Q6P9E5; A8K047

UniProt Related Accession #

P35367

GenBank Nucleotide #

NM_000861.3

NCBI Official Full Name

histamine H1 receptor

NCBI Official Synonym Full Names

histamine receptor H1

NCBI Official Symbol

HRH1

NCBI Official Synonym Symbols

H1R; H1-R; HH1R; hisH1

UniProt Protein Name

Histamine H1 receptor

Protein Family

Histamine H1 receptor

UniProt Gene Name

HRH1

UniProt Synonym Gene Names

H1R; HH1R

NCBI Protein Information

histamine H1 receptor

NCBI Summary for HRH1

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2015]

UniProt Comments for HRH1

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

Research Articles on HRH1

1. H1R and H4R are useful biomarkers of allergic inflammation on the ocular surface. Most notably, H4R expressed on eosinophils is useful as a biomarker of eosinophilic inflammation of the ocular surface.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HRH1 elisa kit

Products by Pathway	Pathway Diagram
Amine Ligand-binding Receptors Pathway antibodies	Amine Ligand-binding Receptors Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Histamine Receptors Pathway antibodies	Histamine Receptors Pathway Diagram

Diseases associated with HRH1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with HRH1 and Nervous System Diseases
Hypersensitivity Antibodies	>4 publications with HRH1 and Hypersensitivity
Urticaria Antibodies	>2 publications with HRH1 and Urticaria
Pain Antibodies	>2 publications with HRH1 and Pain
Bipolar Disorder Antibodies	>1 publications with HRH1 and Bipolar Disorder
Drug Toxicity Antibodies	>1 publications with HRH1 and Drug Toxicity
Seizures Antibodies	>1 publications with HRH1 and Seizures
Respiratory Hypersensitivity Antibodies	>1 publications with HRH1 and Respiratory Hypersensitivity
Schizophrenia Antibodies	>1 publications with HRH1 and Schizophrenia

Organs/Tissues associated with HRH1 elisa kit

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>5 publications with HRH1 and Vascular
Brain Antibodies	>4 publications with HRH1 and Brain
Testis Antibodies	>2 publications with HRH1 and Testis
Lung Antibodies	>2 publications with HRH1 and Lung
Liver Antibodies	>2 publications with HRH1 and Liver
Skin Antibodies	>1 publications with HRH1 and Skin
Trachea Antibodies	>1 publications with HRH1 and Trachea
Connective Tissue Antibodies	>1 publications with HRH1 and Connective Tissue
Adrenal Gland Antibodies	>1 publications with HRH1 and Adrenal Gland