• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AKT3/PKBg Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS462008

Akt [also known as PKB (Protein kinase B) is a family of serine/threonine kinases that plays an important role in signal transduction. There are three known isoforms of Akt in mammalian cells [Akt1 (alpha), Akt2 (beta) and Akt3 (gamma)]; Akt2 and Akt3 have… More details

$315 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AKT3/PKBg, Antibody
Full Product Name
Rabbit anti AKT3/PKBgamma antibody
Product Gene Name
Product Synonym Names
Rabbit anti-AKT3
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Form/Format
This affinity purified antibody is supplied in sterile phosphate-buffered saline (pH7.2) containing antibody stabilizer
Purity/Purification
The Rabbit IgG is purified by Epitope affinity purification
Concentration
Size: 100 ug/200 ul (lot specific)
Specificity
This antibody only recognizes ~56 kDa of human AKT3, not AKT1 or AKT2. It also reacts with mouse and rat AKT3 protein. The other species are not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
56 kDa
Chromosome Location
Chromosome: 1; NC_000001.10 (243651535..244006553, complement). Location: 1q44
3D Structure
ModBase 3D Structure for Q56A86
Antigen Preparation
A synthetic peptide corresponding to the intra domain 120-132aa of human AKT3 protein.
Positive Control
Hela lysate
Cellular Location
Cytoplasmic or membrane
Applications Tested/Suitable for anti-AKT3/PKBg antibody
ELISA, Western Blot, Immunohistochemistry
Application Notes for anti-AKT3/PKBg antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 0.5-2 ug/ml

Testing Data of anti-AKT3/PKBg antibody

Rabbit Anti-AKT3/PKBg Antibody – Cat# MBS462008

Product References and Citations for anti-AKT3/PKBg antibody

Kaname Nakatani, et al. Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines. THE JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 274, No. 31, Issue of July 30, pp. 21528-21532, 1999.

Other Notes

Small volumes of anti-AKT3/PKBg antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKT3/PKBg purchase

MBS462008 is an antibody targeting AKT3/PKBg. Also known as Rabbit anti AKT3/PKBgamma antibody. Reactive in Human, Rat, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AKT3/PKBg. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
AKT3 protein
NCBI Official Synonym Full Names
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
NCBI Official Symbol
AKT3
NCBI Official Synonym Symbols
PKBG; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma; DKFZp434N0250
UniProt Protein Name
AKT3 protein
UniProt Gene Name
AKT3
UniProt Entry Name
Q56A86_HUMAN
NCBI Protein Information
RAC-gamma serine/threonine-protein kinase; PKB gamma; OTTHUMP00000037911; OTTHUMP00000037912; protein kinase Akt-3; protein kinase B gamma; serine threonine protein kinase, Akt-3; RAC-gamma serine/threonine protein kinase

NCBI Summary for AKT3/PKBg

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
Show more

UniProt Comments for AKT3/PKBg

Catalytic activity: ATP + a protein = ADP + a phosphoprotein. SAAS SAAS000961

Sequence similarities: Contains 1 AGC-kinase C-terminal domain. SAAS SAAS000961Contains 1 PH domain. RuleBase RU003350 SAAS SAAS000961

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000