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Moesin (MSN) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475625

Entrez Summary: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is… More details

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Product Overview

Product Name
Moesin (MSN), Monoclonal Antibody
Full Product Name
Anti-Moesin Mouse mAb
Product Gene Name
Product Synonym Names
Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin; Moesin/anaplastic lymphoma kinase fusion protein; Msn; MSN/ALK fusion
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2C12-D10-F1
Host
Mouse
Source: Human
Species Reactivity
Human, Monkey
Sensitivity
The antibody detects endogenous level of total Moesin protein.
Form/Format
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
Purity/Purification
Affinity Purified
Concentration
1mg/ml (lot specific)
Molecular Weight
67.8
OMIM
M69066 mRNA
3D Structure
ModBase 3D Structure for P26038
Immunogen
Purified recombinant fragment of human Moesin expressed in E Coli.
Sequence Similarities
Contains 1 FERM domain.
Subunit Structure
In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation. Binds SLC9A3R1. Interacts with PPP1R16B. Interacts with PDZD8. Interacts with SELPLG and SYK; mediates the activation of SYK by SELPLG.
Subcellular Location
Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphory
Applications Tested/Suitable for anti-MSN antibody
Western Blot (WB)
Application Notes for anti-MSN antibody
WB: 1:1000

Western Blot (WB) of anti-MSN antibody

Western blot detection of Moesin in COS7, Jurkat, HaCat and Hela cell lysates using Moesin mouse mAb (dilution 1:1000).Predicted band size:67.8KDa.Observed band size:67.8KDa.
Mouse Anti-MSN Monoclonal Antibody – Cat# MBS475625

Other Notes

Small volumes of anti-MSN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSN purchase

MBS475625 is an antibody targeting MSN. Also known as Anti-Moesin Mouse mAb. Reactive in Human, Monkey. Host: Mouse
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for MSN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
moesin
NCBI Official Synonym Full Names
moesin
NCBI Official Symbol
MSN
NCBI Official Synonym Symbols
HEL70; IMD50
UniProt Protein Name
Moesin
UniProt Synonym Protein Names
Membrane-organizing extension spike protein
Protein Family
UniProt Gene Name
MSN
NCBI Protein Information
moesin

NCBI Summary for MSN

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
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UniProt Comments for MSN

Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MSN antibody

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