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GABPA Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475824

Entrez Summary: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the… More details

$525 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GABPA, Monoclonal Antibody
Full Product Name
Anti-GABPA Mouse mAb
Product Gene Name
Product Synonym Gene Name
NFT2; NRF2
Product Synonym Names
NFT2; NRF2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C1B10
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
51
OMIM
D13318 mRNA
Immunogen
Purified recombinant fragment of human GABPA (aa120-190) expressed in E Coli.
Applications Tested/Suitable for anti-GABPA antibody
Western Blot (WB), Immunocytochemistry (ICC)

Western Blot (WB) of anti-GABPA antibody

Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2).
Mouse Anti-GABPA Monoclonal Antibody – Cat# MBS475824

Western Blot (WB) of anti-GABPA antibody

Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate.
Mouse Anti-GABPA Monoclonal Antibody, Western Blot (WB) – Cat# MBS475824

Immunofluorescence (IF) of anti-GABPA antibody

Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (green). Red
Mouse Anti-GABPA Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS475824

Other Notes

Small volumes of anti-GABPA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GABPA purchase

MBS475824 is an antibody targeting GABPA. Also known as Anti-GABPA Mouse mAb. Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GABPA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
GABPA
NCBI Official Synonym Full Names
GA binding protein transcription factor alpha subunit
NCBI Official Symbol
GABPA
NCBI Official Synonym Symbols
NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07
UniProt Protein Name
GA-binding protein alpha chain
UniProt Synonym Protein Names
Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60
Protein Family
UniProt Gene Name
GABPA
UniProt Synonym Gene Names
E4TF1A; GABP subunit alpha
NCBI Protein Information
GA-binding protein alpha chain

NCBI Summary for GABPA

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
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UniProt Comments for GABPA

GABPA: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. Belongs to the ETS family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: nuclear chromatin; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor activity

Biological Process: cell differentiation; mitochondrion organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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