• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Lamin B1 (LMNB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477716

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Lamin B1 (LMNB), Polyclonal Antibody
Full Product Name
Anti-Lamin B1 Rabbit pAb
Product Gene Name
Product Synonym Names
LMN; ADLD; LMN2; Lamin B1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
Lamin B1 Antibody detects endogenous levels of total Lamin B1
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
70kDa
OMIM
150340
3D Structure
ModBase 3D Structure for P20700
Immunogen
A synthesized peptide derived from human Lamin B1
Subcellular Location
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side
Applications Tested/Suitable for anti-LMNB antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes for anti-LMNB antibody
WB: 1:3000-1:10000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IP: 1:50

Western Blot (WB) of anti-LMNB antibody

Western blot analysis of Lamin B1 expression in (1) Hela cell lysate; (2) Jurkat cell lysate; (3) Mouse brain lysate; (4) Rat heart lysate with Lamin B1 Antibody.
Rabbit Anti-LMNB Polyclonal Antibody – Cat# MBS477716

Immunohistochemistry (IHC) of anti-LMNB antibody

Immunohistochemical analysis of paraffin-embedded rat liver, using Lamin B1 Antibody.
Rabbit Anti-LMNB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477716

Immunofluorescence (IF) of anti-LMNB antibody

Immunofluorescent analysis of HepG2 cells, using Lamin B1 Antibody.
Rabbit Anti-LMNB Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS477716

Other Notes

Small volumes of anti-LMNB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LMNB purchase

MBS477716 is an antibody targeting LMNB. Also known as Anti-Lamin B1 Rabbit pAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LMNB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lamin-B1 isoform 1
NCBI Official Synonym Full Names
lamin B1
NCBI Official Symbol
LMNB1
NCBI Official Synonym Symbols
LMN; ADLD; LMN2; LMNB
UniProt Protein Name
Lamin-B1
Protein Family
UniProt Gene Name
LMNB1
UniProt Synonym Gene Names
LMN2; LMNB
NCBI Protein Information
lamin-B1

NCBI Summary for LMNB

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

UniProt Comments for LMNB

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LMNB antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000