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CD48 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS520173

PE anti-rat CD45 (Blast-1) monoclonal antibody recognizes a rat cell surface glycoprotein of 45 kDa that is present on a wide variety of hematopoietic cells and on endothelial cells. The antigen is identical to the mouse BCM1 antigen. This antibody inhibits… More details

$365 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD48, Monoclonal Antibody
Full Product Name
Anti-Rat CD48 Purified (Clone OX-45) (mouse IgG1)
Product Gene Name
Product Synonym Names
CD48 Purified (Clone OX-45) (mouse IgG1); PE Anti-Rat CD48 Monoclonal Antibody
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
OX-45
Host
Mouse
Species Reactivity
Rat
Form/Format
PE (PE conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascites supernatant via Protein G Chromatography))
Concentration
Antibody Concentration: 0.1 mg/ml (lot specific)
Specificity
CD48 (Blast-1) (Rat CD48)
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. Avoid prolonged exposure to light
Molecular Weight
27,683 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (160648536..160681641, complement). Location: 1q21.3-q22
OMIM
109530
3D Structure
ModBase 3D Structure for P09326
Immunogen
rat T cell blasts (stimulated purified T helper cells with allogeneic irradiated rat spleen cells)
Donor
BALB/c spleen
Fusion Partner
myeloma cell line NSO/1
Presentation
50 ug or 200 ug R-PE conjugated Ig buffered in PBS, 0.1% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Applications Tested/Suitable for anti-CD48 antibody
Immunohistochemistry (IHC)

Testing Data of anti-CD48 antibody

Mouse Anti-CD48 Monoclonal Antibody – Cat# MBS520173

Other Notes

Small volumes of anti-CD48 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD48 purchase

MBS520173 is an antibody targeting CD48. Also known as Anti-Rat CD48 Purified (Clone OX-45) (mouse IgG1). Reactive in Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD48. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CD48 antigen isoform 1
NCBI Official Synonym Full Names
CD48 molecule
NCBI Official Symbol
CD48
NCBI Official Synonym Symbols
BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102
UniProt Protein Name
CD48 antigen
UniProt Synonym Protein Names
B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1
Protein Family
UniProt Gene Name
CD48
UniProt Synonym Gene Names
BCM1; BLAST1; SLAMF2
UniProt Entry Name
CD48_HUMAN
NCBI Protein Information
CD48 antigen; TCT.1; BCM1 surface antigen; SLAM family member 2; leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen (B-cell membrane protein); signaling lymphocytic activation molecule 2

NCBI Summary for CD48

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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UniProt Comments for CD48

Function: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

Subunit structure: Interacts with CD244 in an heterophilic manner

By similarity.

Subcellular location: Cell membrane; Lipid-anchor › GPI-anchor.

Sequence similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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