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APBB3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS533410

MBS533410 is an antibody targeting APBB3. Also known as APBB3 antibody. Host: Mouse. Mouse monoclonal APBB3 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APBB3, Monoclonal Antibody
Full Product Name
APBB3 antibody
Product Gene Name
Product Synonym Names
Monoclonal APBB3; Anti-APBB3; Amyloid Beta A4 Precursor Protein-Binding 3B; FE65L2; MGC150555; MGC87674; SRA; APBB3; APBB 3; APBB-3
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5G3
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
APBB3 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
26,460 Da
OMIM
602711
3D Structure
ModBase 3D Structure for O95704
Cross-Reactivity
Human
Immunogen
APBB3 antibody was raised in mouse using a full length human recombinan protein of human APBB3 (NP_573419) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-APBB3 antibody

Applications Tested/Suitable for anti-APBB3 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-APBB3 antibody
FC: 1:100
IHC: 1:150
WB: 1:500

Western Blot (WB) of anti-APBB3 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant APBB3 protein (Right) or empty vector (Left) detected with APBB3 antibody
Mouse Anti-APBB3 Monoclonal Antibody – Cat# MBS533410

Immunohistochemistry (IHC) of anti-APBB3 antibody

Immunohistochemical analysis of APBB3 protein in paraffin embedded Human colon tissue using APBB3 antibody
Mouse Anti-APBB3 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS533410

Other Notes

Small volumes of anti-APBB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APBB3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
amyloid beta A4 protein-binding family B member 3 isoform b
NCBI Official Synonym Full Names
amyloid beta (A4) precursor protein-binding, family B, member 3
NCBI Official Symbol
APBB3
NCBI Official Synonym Symbols
SRA; FE65L2
UniProt Protein Name
Amyloid beta A4 precursor protein-binding family B member 3
UniProt Synonym Protein Names
Protein Fe65-like 2; Fe65L2
UniProt Gene Name
APBB3
UniProt Synonym Gene Names
FE65L2; Fe65L2
UniProt Entry Name
APBB3_HUMAN
NCBI Protein Information
amyloid beta A4 precursor protein-binding family B member 3

NCBI Summary for APBB3

The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for APBB3

APBB3: May modulate the internalization of beta-amyloid precursor protein. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: cytoplasm; nucleus; actin cytoskeleton

Molecular Function: protein binding; beta-amyloid binding; transcription factor binding

Biological Process: regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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