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Histidine Decarboxylase (HDC) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS535374

MBS535374 is an antibody targeting HDC. Also known as Histidine Decarboxylase antibody. Reactive in Dog, Guinea Pig, Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal Histidine Decarboxylase antibody More details

$1850 / 0.05 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Histidine Decarboxylase (HDC), Polyclonal Antibody
Full Product Name
Histidine Decarboxylase antibody
Product Gene Name
Product Synonym Names
Polyclonal Histidine Decarboxylase; Anti-Histidine Decarboxylase; HDC
Clonality
Polyclonal
Isotype
IgG1
Host
Rabbit
Species Reactivity
Dog, Guinea Pig, Human, Mouse, Rat
Form/Format
Supplied as a lyophilized powder. Dissolve the antiserum in 50 - 100 ul distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% NaN3.
Purity/Purification
Whole antiserum
Specificity
E Coli histidine decarboxylase
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
Molecular Weight
70,059 Da
OMIM
142704
3D Structure
ModBase 3D Structure for P19113
Cross-Reactivity
Dog, guinea pig, human, mouse, rat
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
Histidine decarboxylase antibody was raised in rabbit using recombinant histidine decarboxylase produced in E Coli as the immunogen.

Product Categories/Family for anti-HDC antibody

Applications Tested/Suitable for anti-HDC antibody
Immunofluorescence (IF)
Application Notes for anti-HDC antibody
IF: 1:1,000-1:1,500

Other Notes

Small volumes of anti-HDC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HDC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histidine decarboxylase isoform 1
NCBI Official Synonym Full Names
histidine decarboxylase
NCBI Official Symbol
HDC
UniProt Protein Name
Histidine decarboxylase
Protein Family
UniProt Gene Name
HDC
UniProt Synonym Gene Names
HDC
UniProt Entry Name
DCHS_HUMAN
NCBI Protein Information
histidine decarboxylase

NCBI Summary for HDC

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]
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UniProt Comments for HDC

HDC: a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]

Protein type: Lyase; EC 4.1.1.22; Amino Acid Metabolism - histidine

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: cytosol

Molecular Function: pyridoxal phosphate binding; histidine decarboxylase activity

Biological Process: catecholamine biosynthetic process; histamine biosynthetic process; histidine metabolic process; histidine catabolic process

Disease: Gilles De La Tourette Syndrome
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HDC antibody

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