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MDC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS535775

MBS535775 is an antibody targeting MDC. Also known as MDC antibody. Reactive in Murine MDC. Host: Rabbit. Affinity purified Rabbit polyclonal MDC antibody More details

$685 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MDC, Polyclonal Antibody
Full Product Name
MDC antibody
Product Gene Name
Product Synonym Names
Polyclonal MDC; Anti-MDC; STCP-1; Macrophage-Derived Chemokine; ABCD-1; CCL22
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Murine MDC
Form/Format
Lyophilized from PBS, pH 7.2.
Specificity
Murine MDC
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
7.8 kDa (predicted detection band MW)
OMIM
155120
Immunogen
MDC antibody was raised in rabbit using highly pure recombinant murine MDC as the immunogen.
Applications Tested/Suitable for anti-MDC antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes for anti-MDC antibody
ELISA: 0.5-2 ug/ml
Inhibition: 6-9 ug/ml
WB: 0.1-0.2 ug/ml

Other Notes

Small volumes of anti-MDC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MDC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Secondary Accession #
NCBI Official Full Name
MDC protein
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 11
UniProt Synonym Protein Names
Metalloproteinase-like, disintegrin-like, and cysteine-rich protein; MDC
UniProt Gene Name
ADAM11
UniProt Synonym Gene Names
MDC; ADAM 11; MDC
UniProt Entry Name
ADA11_HUMAN

NCBI Summary for MDC

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Dec 2014]
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UniProt Comments for MDC

ADAM11: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: extracellular matrix; plasma membrane; integral to membrane

Molecular Function: integrin binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: integrin-mediated signaling pathway; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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