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Alpha Actinin (ACTN3) Native Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536612

MBS536612 is a native protein targeting ACTN3. Also known as alpha Actinin protein. Host: Chicken. Purified native Chicken alpha Actinin protein More details

$1405 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
alpha Actinin (ACTN3), Native Protein
Full Product Name
alpha Actinin protein
Product Gene Name
Product Synonym Names
alpha Actinin 1 protein; ACTN1 protein; FLJ40884 protein
Host
Chicken
Form/Format
Supplied in lyophilized form with 10 mM Tris/HCl buffer pH 8.0, 0.2mM CaCl2, 0.2 mM ATP, 1 mM DTT, 0.5% (w/v) SDS
Purity/Purification
> 95% pure
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 2-8 degree C in lyophilized form. Following reconstitution aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
95 kDa
OMIM
102574
3D Structure
ModBase 3D Structure for Q08043
Source Note
Chicken gizzard
Protein Type
Native

Product Categories/Family for ACTN3 native protein

Applications Tested/Suitable for ACTN3 native protein
User optimized

Other Notes

Small volumes of ACTN3 native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACTN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
alpha-actinin
NCBI Official Synonym Full Names
actinin, alpha 3 (gene/pseudogene)
NCBI Official Symbol
ACTN3
UniProt Protein Name
Alpha-actinin-3
UniProt Synonym Protein Names
Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
Protein Family
UniProt Gene Name
ACTN3
UniProt Entry Name
ACTN3_HUMAN
NCBI Protein Information
alpha-actinin-3

NCBI Summary for ACTN3

This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014]
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UniProt Comments for ACTN3

ACTN3: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Belongs to the alpha-actinin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: focal adhesion; actin filament; pseudopodium; cytosol

Molecular Function: integrin binding; protein binding; protein homodimerization activity; structural constituent of muscle; calcium ion binding; actin binding

Biological Process: focal adhesion formation; regulation of apoptosis; muscle filament sliding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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