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Bone Marrow Stromal Cell Antigen 1 (BST1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540009

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bone marrow stromal cell antigen 1 (BST1), Polyclonal Antibody
Full Product Name
Bone marrow stromal cell antigen 1 Antibody
Product Gene Name
Product Synonym Names
ADP ribosyl cyclase 2; Bone marrow stromal antigen 1; BST 1; cADPr hydrolase 2; CD157; Cyclic ADP ribose hydrolase 2; NAD(+) nucleosidase antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.68 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Molecular Weight
29,326 Da
OMIM
600387
3D Structure
ModBase 3D Structure for Q10588
Immunogen
Synthetic peptide corresponding to amino acids 255-274 of Human Bone marrow stromal cell antigen 1. Peptide was covalently modified.
Sequence: FQY SCI NDY RPV KLL QCV DH
Expression
Widely Expressed
Molecular Function
Hydrolase, Transferase
Structure
Homodimer
Subcellular Location
Cell Membrane
Applications Tested/Suitable for anti-BST1 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-BST1 antibody
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500

Western Blot (WB) of anti-BST1 antibody

Rabbit Anti-BST1 Polyclonal Antibody – Cat# MBS540009

Western Blot (WB) of anti-BST1 antibody

Rabbit Anti-BST1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS540009

Other Notes

Small volumes of anti-BST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BST1 purchase

MBS540009 is an antibody targeting BST1. Also known as Bone marrow stromal cell antigen 1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BST1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Bone marrow stromal cell antigen 1
NCBI Official Synonym Full Names
bone marrow stromal cell antigen 1
NCBI Official Symbol
BST1
NCBI Official Synonym Symbols
CD157
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Synonym Protein Names
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157
UniProt Gene Name
BST1
UniProt Synonym Gene Names
BST-1; cADPr hydrolase 2
UniProt Entry Name
BST1_HUMAN
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

NCBI Summary for BST1

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
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UniProt Comments for BST1

BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family.

Protein type: Membrane protein, GPI anchor; Hydrolase; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.2.2.6

Chromosomal Location of Human Ortholog: 4p15

Cellular Component: extrinsic to membrane; plasma membrane

Molecular Function: NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; phosphorus-oxygen lyase activity; transferase activity

Biological Process: humoral immune response; metabolic process; multicellular organismal development; positive regulation of B cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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