Rabbit Anti-ADCY1 Polyclonal Antibody – Cat# MBS540151

WB of MBS540151 with MBS543021 1:500 antibody dilution in DiluObuffer.

Adenylate Cyclase 1 (ADCY1) Antibody – Rabbit Polyclonal

Name: ADCY1 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS540151
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540151

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast… More details

$540 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Adenylate cyclase 1 (Adcy1), Polyclonal Antibody

Full Product Name

Adenylate Cyclase 1 Antibody

Product Gene Name

anti-Adcy1 antibody

Product Synonym Names

3'5' cyclic AMP synthetase; ADCY1; adenyl cyclase; Adenylate cyclase 1; ATP pyrophosphate lyase; Brain adenylate cyclase 1; Ca(2+)/calmodulin activated adenylyl cyclase; EC 4.6.1.1 antibody

Clonality

Polyclonal

Host

Rabbit

Form/Format

Affinity Purified Immunoglobulins

Concentration

0.72 mg/ml (lot specific)

Preparation and Storage

Store at -20°C for long term storage.

3D Structure

ModBase 3D Structure for O88444

Immunogen

Synthetic peptide taken with amino acids region 1030-1060 on rat/mouse Adeylyl Cyclase 1 protein.

Immunoglobulin

IgG in antibody stabilization buffer.

Molecular Function

ATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-binding

Structure

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains

Subcellular Location

Membrane; Multi-pass membrane protein. Cytoplasm

Species Cross Reactivity

Mouse, Rabbit, Rat

Product Categories/Family for anti-Adcy1 antibody

Primary Antibodies; Signal Transduction; G-Protein Coupled Receptors; Adenylate cyclase 1 Antibody

Applications Tested/Suitable for anti-Adcy1 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-Adcy1 antibody

ELISA: 1:10,000
DOT Blot: 1:10,000
Western Blot: 1:500.

Other Notes

Small volumes of anti-Adcy1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adcy1 purchase

MBS540151 is an antibody targeting Adcy1. Also known as Adenylate Cyclase 1 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Adcy1. It may not necessarily be applicable to this product.

NCBI GI #

3406745

NCBI GeneID

432530

NCBI Accession #

AAC29478

UniProt Primary Accession #

O88444

UniProt Secondary Accession #

Q5SS89

UniProt Related Accession #

O88444

NCBI Official Full Name

adenylyl cyclase type I, partial

NCBI Official Synonym Full Names

adenylate cyclase 1

NCBI Official Symbol

Adcy1

NCBI Official Synonym Symbols

AC1; brl; I-AC; mKIAA4070; D11Bwg1392e

UniProt Protein Name

Adenylate cyclase type 1

UniProt Synonym Protein Names

ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase

Protein Family

Adenylate cyclase

UniProt Gene Name

Adcy1

UniProt Entry Name

ADCY1_MOUSE

NCBI Protein Information

adenylate cyclase type 1

UniProt Comments for Adcy1

ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Adenylyl cyclase; Transporter; Lyase; Membrane protein, multi-pass; Membrane protein, integral; EC 4.6.1.1; Nucleotide Metabolism - purine; Transporter, aquaporin family

Cellular Component: cytoplasm; integral to membrane; membrane; nucleus; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; lyase activity; metal ion binding; nucleotide binding; phosphorus-oxygen lyase activity

Biological Process: adenylate cyclase activation; axonogenesis; cAMP biosynthetic process; cAMP-mediated signaling; cyclic nucleotide biosynthetic process; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; long-term memory; regulation of circadian rhythm; rhythmic process

Research Articles on Adcy1

1. Findings provide evidence to link activation of alpha7 nAChRs to a cAMP rise via AC1, which defines a new signaling pathway employed by alpha7 nAChRs

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Adcy1 antibody

Products by Pathway	Pathway Diagram
Activation Of GABAB Receptors Pathway antibodies	Activation Of GABAB Receptors Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Adenylate Cyclase Activating Pathway antibodies	Adenylate Cyclase Activating Pathway Diagram
Adenylate Cyclase Inhibitory Pathway antibodies	Adenylate Cyclase Inhibitory Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Aldosterone Synthesis And Secretion Pathway antibodies	Aldosterone Synthesis And Secretion Pathway Diagram
Aldosterone Synthesis And Secretion Pathway antibodies	Aldosterone Synthesis And Secretion Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram

Diseases associated with anti-Adcy1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>6 publications with Adcy1 and Nervous System Diseases
Brain Diseases Antibodies	>3 publications with Adcy1 and Brain Diseases
Depressive Disorder Antibodies	>2 publications with Adcy1 and Depressive Disorder
Hyperglycemia Antibodies	>1 publications with Adcy1 and Hyperglycemia
Abnormalities, Drug-Induced Antibodies	>1 publications with Adcy1 and Abnormalities, Drug-Induced
Cell Transformation, Neoplastic Antibodies	>1 publications with Adcy1 and Cell Transformation, Neoplastic
Glucose Intolerance Antibodies	>1 publications with Adcy1 and Glucose Intolerance

Organs/Tissues associated with anti-Adcy1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>16 publications with Adcy1 and Brain
Eye Antibodies	>8 publications with Adcy1 and Eye
Embryonic Tissue Antibodies	>3 publications with Adcy1 and Embryonic Tissue
Pancreas Antibodies	>2 publications with Adcy1 and Pancreas
Spinal Cord Antibodies	>1 publications with Adcy1 and Spinal Cord
Inner Ear Antibodies	>1 publications with Adcy1 and Inner Ear
Skin Antibodies	>1 publications with Adcy1 and Skin