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ARF4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541012

FITC-Conjugated ADP-ribosylation factor 4 AntibodyGTP-binding protein that functions as an allosteric activator of cholera toxin catalytic subunt. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARF4, Polyclonal Antibody
Full Product Name
ARF4 Antibody FITC-Conjugated
Product Gene Name
anti-ARF4 antibody
Product Synonym Names
ADP ribosylation factor 2; ADP ribosylation factor 4 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
FITC-Conjugated
Concentration
0.71-0.75 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
ARF4 peptide (MBS542389) is used for blocking the activity of ARF4 antibody (MBS541012)
Matching Pairs
Antibody: ARF4 (MBS541012)
Positive Control: ARF4 (MBS542545)
Molecular Weight
20,397 Da
3D Structure
ModBase 3D Structure for P61751
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on ARF4 protein.
Expression
Cell junction; Membrane; Synapse
Molecular Function
ADP-ribosyltransferase; GTP binding; ER-Golgi transport
Structure
Belongs to the small GTPase superfamily, Arf family
Subcellular Location
Gogli apparatus
Applications Tested/Suitable for anti-ARF4 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-ARF4 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-ARF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARF4 purchase

MBS541012 is an antibody targeting ARF4. Also known as ARF4 Antibody FITC-Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARF4. It may not necessarily be applicable to this product.

NCBI GI #
48428789
NCBI GeneID
79120
NCBI Accession #
P61751.2
UniProt Primary Accession #
P61751
UniProt Secondary Accession #
P36403
UniProt Related Accession #
P61751
NCBI Official Full Name
ADP-ribosylation factor 4
NCBI Official Synonym Full Names
ADP-ribosylation factor 4
NCBI Official Symbol
Arf4
UniProt Protein Name
ADP-ribosylation factor 4
Protein Family
ADP-ribosylation factor
UniProt Gene Name
Arf4
UniProt Entry Name
ARF4_RAT
NCBI Protein Information
ADP-ribosylation factor 4

NCBI Summary for ARF4

human homolog binds EGFR and mediates the EGF-dependent activation of phospholipase D2 (PLD2) and of transcription factor AP-1 [RGD, Feb 2006]

UniProt Comments for ARF4

ARF4: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric, ARF; G protein; G protein, monomeric

Cellular Component: cytoplasm; cytosol; dendritic spine; Golgi apparatus; membrane; plasma membrane

Molecular Function: epidermal growth factor receptor binding; GTP binding

Biological Process: apical protein localization; brain development; cell migration; epidermal growth factor receptor signaling pathway; establishment and/or maintenance of epithelial cell polarity; learning; negative regulation of apoptosis; phospholipase D activation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid ADP-ribosylation; protein transport; response to axon injury; retrograde vesicle-mediated transport, Golgi to ER; small GTPase mediated signal transduction; vesicle-mediated transport
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Research Articles on ARF4

1. a functional role for CAPS1 in regulating DCV trafficking in the trans-Golgi network; this activity occurs via protein-protein interaction with ARF4/ARF5 in a GDP-dependent manner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ARF4 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 COPI-dependent Golgi-to-ER Retrograde Traffic Pathway antibodies  COPI-dependent Golgi-to-ER Retrograde Traffic Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Golgi-to-ER Retrograde Transport Pathway antibodies  Golgi-to-ER Retrograde Transport Pathway Diagram
 Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway antibodies  Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram

Diseases associated with anti-ARF4 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >3 publications with ARF4 and Kidney Diseases
 Poisoning Antibodies  >1 publications with ARF4 and Poisoning
 Inflammation Antibodies  >1 publications with ARF4 and Inflammation
 Weight Loss Antibodies  >1 publications with ARF4 and Weight Loss

Organs/Tissues associated with anti-ARF4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with ARF4 and Brain
 Kidney Antibodies  >8 publications with ARF4 and Kidney
 Heart Antibodies  >6 publications with ARF4 and Heart
 Lung Antibodies  >4 publications with ARF4 and Lung
 Eye Antibodies  >4 publications with ARF4 and Eye
 Ovary Antibodies  >2 publications with ARF4 and Ovary
 Liver Antibodies  >2 publications with ARF4 and Liver
 Spleen Antibodies  >2 publications with ARF4 and Spleen
 Placenta Antibodies  >2 publications with ARF4 and Placenta
 Pancreas Antibodies  >1 publications with ARF4 and Pancreas
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