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GARP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541306

FITC-Conjugated cyclic nucleotide-gated cation channel beta-1 AntibodyInvolved in cGMP binding and sensory perception. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GARP, Polyclonal Antibody
Full Product Name
GARP Antibody FITC-Conjugated
Product Gene Name
anti-GARP antibody
Product Synonym Names
CNCG2; CNCG3L; CNCG4; CNG channel 4; CNG channel beta 1; CNGB1B; Cyclic nucleotide gated cation channel modulatory subunit; Cyclic nucleotide gated channel (photoreceptor) cGMP gated 3 (gamma) like; GAR1; Glutamic acid rich protein; RCNC2; RP45 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
FITC-Conjugated
Concentration
0.55-0.60 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: GARP (MBS541306)
Positive Control: GARP (MBS542643)
Antibody/Peptide Pairs
GARP peptide (MBS542986) is used for blocking the activity of GARP antibody (MBS541306)
Molecular Weight
151,047 Da
3D Structure
ModBase 3D Structure for O35788
Immunogen
Synthetic peptide taken within amino acid region 1310-1345 on rat CNGb1 protein.
Subcellular Location
Integral component of Plasma membrane; terminal bouton
Applications Tested/Suitable for anti-GARP antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-GARP antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500

Other Notes

Small volumes of anti-GARP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GARP purchase

MBS541306 is an antibody targeting GARP. Also known as GARP Antibody FITC-Conjugated. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GARP. It may not necessarily be applicable to this product.

NCBI GI #
13929148
NCBI GeneID
83686
NCBI Accession #
NP_113997.1
UniProt Primary Accession #
O35788
GenBank Nucleotide #
NM_031809.1
NCBI Official Full Name
cyclic nucleotide-gated cation channel beta-1
NCBI Official Synonym Full Names
cyclic nucleotide gated channel beta 1
NCBI Official Symbol
Cngb1
NCBI Official Synonym Symbols
Gm1959
UniProt Protein Name
Cyclic nucleotide-gated channel beta subunit
UniProt Synonym Protein Names
Cyclic nucleotide-gated channel beta subunit
Protein Family
Glutamic acid-rich protein
UniProt Gene Name
Cngb1
UniProt Entry Name
O35788_RAT
NCBI Protein Information
cyclic nucleotide-gated cation channel beta-1

NCBI Summary for GARP

olfactory cyclic nucleotide-gated channel subunit [RGD, Feb 2006]

UniProt Comments for GARP

CNGB1: an integral membrane protein that forms a heterooligomeric complex with CNGA1. A modulatory subunit of cyclic nucleotide-gated cation channels.

Protein type: Channel, cation; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: integral to plasma membrane; intracellular cyclic nucleotide activated cation channel complex; membrane; photoreceptor outer segment; plasma membrane; terminal button

Molecular Function: cGMP binding; cyclic nucleotide-gated ion channel activity; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; intracellular cyclic nucleotide activated cation channel activity; voltage-gated potassium channel activity

Biological Process: cation transport; cytosolic calcium ion homeostasis; detection of light stimulus involved in visual perception; photoreceptor cell maintenance; phototransduction; protein heterotetramerization; protein localization in organelle; regulation of membrane potential; retinal homeostasis; sensory perception of smell; visual perception
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GARP antibody

 Products by Pathway  Pathway Diagram
 Activation Of The Phototransduction Cascade Pathway antibodies  Activation Of The Phototransduction Cascade Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies  Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-GARP antibody

 Disease Name  Pubmed Publications
 Retinitis Pigmentosa Antibodies  >24 publications with GARP and Retinitis Pigmentosa
 Disease Models, Animal Antibodies  >10 publications with GARP and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with GARP and Brain Diseases
 Weight Loss Antibodies  >1 publications with GARP and Weight Loss

Organs/Tissues associated with anti-GARP antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >45 publications with GARP and Eye
 Brain Antibodies  >6 publications with GARP and Brain
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