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PARD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS542387

FITC-Conjugated Proteinase-activated receptor 4 precursor AntibodyFunctions as a receptor for activated thrombin or trypsin coupled to G-proteins that stimulate phosphoinositide hydrolysis.  May also function in contributing to the activation of platelets. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PARD3, Polyclonal Antibody
Full Product Name
PARD3 Antibody FITC-Conjugated
Product Gene Name
anti-PARD3 antibody
Product Synonym Names
agouti signaling protein; ASIP; Atypical PKC isotype specific interacting protein; Baz; bazooka; Coagulation factor II receptor-like 2; CTCL tumor antigen se2-5; F2rl2; PAR-3; PAR3-alpha; PARD-3; Partitioning-defective protein 3, C. elegans, homolog of; SE2-5L16; SE2-5LT1; SE2-5T2; Thrombin receptor-like 2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
FITC-Conjugated
Concentration
0.50-0.75 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: PARD3 (MBS542387)
Positive Control: PARD3 (MBS543041)
Antibody/Peptide Pairs
PARD3 peptide (MBS544119) is used for blocking the activity of PARD3 antibody (MBS542387)
Molecular Weight
42,786 Da
3D Structure
ModBase 3D Structure for O88634
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PARD3 protein.
Applications Tested/Suitable for anti-PARD3 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), IMM, Western Blot (WB)
Application Notes for anti-PARD3 antibody
Confocal Microscopy||1:200
Dot Blot: 1:12,000
ELISA: 1:12,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:5,000

Other Notes

Small volumes of anti-PARD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PARD3 purchase

MBS542387 is an antibody targeting PARD3. Also known as PARD3 Antibody FITC-Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PARD3. It may not necessarily be applicable to this product.

NCBI GI #
6679729
NCBI GeneID
14065
NCBI Accession #
NP_032001.1
UniProt Primary Accession #
O88634
UniProt Secondary Accession #
Q8BZ77
UniProt Related Accession #
O88634
GenBank Nucleotide #
NM_007975.1
NCBI Official Full Name
coagulation factor II (thrombin) receptor-like 3
NCBI Official Synonym Full Names
coagulation factor II (thrombin) receptor-like 3
NCBI Official Symbol
F2rl3
NCBI Official Synonym Symbols
PAR4
UniProt Protein Name
Proteinase-activated receptor 4
UniProt Synonym Protein Names
Coagulation factor II receptor-like 3; Thrombin receptor-like 3
Protein Family
Antitoxin
UniProt Gene Name
F2rl3
UniProt Synonym Gene Names
Par4; PAR-4
UniProt Entry Name
PAR4_MOUSE
NCBI Protein Information
proteinase-activated receptor 4

UniProt Comments for PARD3

PAR4: a G-protein coupled receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Plays a role in platelets activation. Thrombin requires PAR4 for full spreading on a fibrinogen matrix. Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Cellular Component: integral to membrane; membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; thrombin receptor activity

Biological Process: blood coagulation; G-protein coupled receptor protein signaling pathway; hemostasis; positive regulation of release of sequestered calcium ion into cytosol; signal transduction
Show more

Research Articles on PARD3

1. Thrombin cleavage of platelet PAR4 promotes leukocyte recruitment to sites of vascular injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PARD3 antibody

 Reference Product  PubMed Publications
 F2rl2 antibody  >1 publications with PARD3 and F2rl2

Pathways associated with anti-PARD3 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-PARD3 antibody

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >2 publications with PARD3 and Lung Diseases
 Hypertension Antibodies  >1 publications with PARD3 and Hypertension
 Inflammation Antibodies  >1 publications with PARD3 and Inflammation

Organs/Tissues associated with anti-PARD3 antibody

 Organ/Tissue Name  Pubmed Publications
 Joint Antibodies  >1 publications with PARD3 and Joint
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