• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Receptor 1 for the Fc Region of Immunoglobulin G (FcgammaRI) ELISA Kit for Canine

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS054974

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of FcGRI (hereafter termed "analyte") in undiluted original Canine body fluids, tissue… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Receptor I For The Fc Region of Immunoglobulin G (FcgammaRI), ELISA Kit
Full Product Name
Canine Receptor I For The Fc Region of Immunoglobulin G ELISA Kit
Product Gene Name
FcgammaRI elisa kit
Species Reactivity
Canine
Assay Type
Sandwich
Samples
Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances
Detection Range
0.625ng/ml-20ng/ml
Sensitivity
0.1ng/ml
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Preparation and Storage
Store all reagents at 2-8 degree C
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Molecular Weight
44,888 Da
3D Structure
ModBase 3D Structure for P26151

Other Notes

Small volumes of FcgammaRI elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FcgammaRI purchase

MBS054974 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Receptor I For The Fc Region of Immunoglobulin G (FcgammaRI) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FcgammaRI. The ELISA analytical biochemical technique of the MBS054974 kit is based on FcgammaRI antibody-FcgammaRI antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FcgammaRI antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FcgammaRI. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FcgammaRI. It may not necessarily be applicable to this product.

NCBI GI #
182888429
NCBI GeneID
14129
NCBI Accession #
AAI60240.1
UniProt Primary Accession #
P26151
UniProt Related Accession #
P26151
NCBI Official Full Name
Fc receptor, IgG, high affinity I
NCBI Official Synonym Full Names
Fc receptor, IgG, high affinity I
NCBI Official Symbol
Fcgr1
NCBI Official Synonym Symbols
CD64; IGGHAFC; AI323638; AV092959; FcgammaRI
UniProt Protein Name
High affinity immunoglobulin gamma Fc receptor I
UniProt Synonym Protein Names
Fc-gamma RI
UniProt Gene Name
Fcgr1
UniProt Synonym Gene Names
Fcg1; IgG Fc receptor I; FcRI
UniProt Entry Name
FCGR1_MOUSE
NCBI Protein Information
high affinity immunoglobulin gamma Fc receptor I; fcRI; fc-gamma RI; igG Fc receptor I; IgG high affinity Fc receptor

UniProt Comments for FcgammaRI

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; plasma membrane; integral to membrane; external side of plasma membrane; lipid raft

Molecular Function: leukotriene receptor binding; IgG binding; IgG receptor activity

Biological Process: receptor-mediated endocytosis; regulation of immune response; immune system process; positive regulation of type III hypersensitivity; phagocytosis, recognition; antigen processing and presentation of exogenous antigen; antibody-dependent cellular cytotoxicity; cell surface receptor linked signal transduction; response to bacterium; positive regulation of type IIa hypersensitivity; positive regulation of phagocytosis; defense response to bacterium; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; phagocytosis, engulfment; positive regulation of phagocytosis, engulfment
Show more

Research Articles on FcgammaRI

1. The PI3K inhibitor LY294002 inhibited BCR-mediated, but not TLR-mediated, induction of IkappaB-zeta, consistent with the role of PI3K in BCR signaling and its suppression by FcgammaR.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FcgammaRI elisa kit

 Reference Product  PubMed Publications
 Icam1 elisa kit  >2 publications with FcgammaRI and Icam1
 Stat1 elisa kit  >2 publications with FcgammaRI and Stat1
 Irf8 elisa kit  >1 publications with FcgammaRI and Irf8

Pathways associated with FcgammaRI elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway antibodies  Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with FcgammaRI elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with FcgammaRI and Inflammation
 Disease Models, Animal Antibodies  >15 publications with FcgammaRI and Disease Models, Animal
 Neoplasms Antibodies  >8 publications with FcgammaRI and Neoplasms
 Lung Diseases Antibodies  >8 publications with FcgammaRI and Lung Diseases
 Lung Neoplasms Antibodies  >3 publications with FcgammaRI and Lung Neoplasms
 Arthritis, Experimental Antibodies  >3 publications with FcgammaRI and Arthritis, Experimental
 Atherosclerosis Antibodies  >2 publications with FcgammaRI and Atherosclerosis
 Kidney Diseases Antibodies  >2 publications with FcgammaRI and Kidney Diseases
 Cognition Disorders Antibodies  >1 publications with FcgammaRI and Cognition Disorders
 Liver Neoplasms, Experimental Antibodies  >1 publications with FcgammaRI and Liver Neoplasms, Experimental

Organs/Tissues associated with FcgammaRI elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with FcgammaRI and Blood
 Bone Antibodies  >12 publications with FcgammaRI and Bone
 Bone Marrow Antibodies  >10 publications with FcgammaRI and Bone Marrow
 Lung Antibodies  >8 publications with FcgammaRI and Lung
 Brain Antibodies  >7 publications with FcgammaRI and Brain
 Joint Antibodies  >5 publications with FcgammaRI and Joint
 Lymph Node Antibodies  >4 publications with FcgammaRI and Lymph Node
 Liver Antibodies  >2 publications with FcgammaRI and Liver
 Thymus Antibodies  >1 publications with FcgammaRI and Thymus
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000