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TRIP10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9125546
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MBS9125546 is an antibody targeting TRIP10. Also known as TRIP10 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRIP10, Polyclonal Antibody
Full Product Name
TRIP10 Polyclonal Antibody
Product Gene Name
anti-TRIP10 antibody
Product Synonym Names
STP; CIP4; HSTP; STOT; TRIP-10
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
601
OMIM
604504
3D Structure
ModBase 3D Structure for Q15642
Species
Human
Immunogen
Recombinant protein of human TRIP10
Calculated Molecular Weight
68kDa

Product Categories/Family for anti-TRIP10 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRIP10 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TRIP10 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100

Western Blot (WB) of anti-TRIP10 antibody

Western blot analysis of extracts of various cell lines, using TRIP10 antibody at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-TRIP10 Polyclonal Antibody – Cat# MBS9125546

Immunofluorescence (IF) of anti-TRIP10 antibody

Immunofluorescence analysis of U2OS cells using TRIP10 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-TRIP10 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS9125546

Other Notes

Small volumes of anti-TRIP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIP10. It may not necessarily be applicable to this product.

NCBI GI #
118572632
NCBI GeneID
9322
NCBI Accession #
Q15642.3
UniProt Primary Accession #
Q15642
UniProt Secondary Accession #
O15184; Q53G22; Q5TZN1; Q6FI24; Q8NFL1; Q8TCY1; Q8TDX3; Q96RJ1; B2R8A6; B7WP22; D6W645
UniProt Related Accession #
Q15642
NCBI Official Full Name
Cdc42-interacting protein 4
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 10
NCBI Official Symbol
TRIP10
NCBI Official Synonym Symbols
STP; CIP4; HSTP; STOT; TRIP-10
UniProt Protein Name
Cdc42-interacting protein 4
UniProt Synonym Protein Names
Protein Felic; Salt tolerant protein; hSTP; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Protein Family
Cdc42-interacting protein
UniProt Gene Name
TRIP10
UniProt Synonym Gene Names
CIP4; STOT; STP; hSTP; TR-interacting protein 10; TRIP-10
UniProt Entry Name
CIP4_HUMAN
NCBI Protein Information
cdc42-interacting protein 4; protein Felic; salt tolerator; salt tolerant protein; TR-interacting protein 10; thyroid receptor-interacting protein 10

UniProt Comments for TRIP10

TRIP10: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. Belongs to the FNBP1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cell projection; cytoskeleton; intracellular membrane-bound organelle; perinuclear region of cytoplasm; lysosome; cytoplasm; cell cortex; cytosol; phagocytic cup

Molecular Function: identical protein binding; protein binding; lipid binding

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; endocytosis; cell communication; signal transduction; actin cytoskeleton organization and biogenesis
Show more

Research Articles on TRIP10

1. CIP4 controls cell-cell cohesion and is required for the acquisition of an invasive phenotype in breast tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TRIP10 antibody

 Products by Pathway  Pathway Diagram
 Insulin Pathway antibodies  Insulin Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin-mediated Glucose Transport Pathway antibodies  Insulin-mediated Glucose Transport Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with anti-TRIP10 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >3 publications with TRIP10 and Immune System Diseases
 Hypertension Antibodies  >3 publications with TRIP10 and Hypertension
 Nervous System Diseases Antibodies  >2 publications with TRIP10 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with TRIP10 and Brain Diseases
 Liver Neoplasms Antibodies  >2 publications with TRIP10 and Liver Neoplasms
 Lung Diseases Antibodies  >1 publications with TRIP10 and Lung Diseases
 Cognition Disorders Antibodies  >1 publications with TRIP10 and Cognition Disorders
 Blood Coagulation Disorders Antibodies  >1 publications with TRIP10 and Blood Coagulation Disorders
 Fibrosis Antibodies  >1 publications with TRIP10 and Fibrosis
 Lung Neoplasms Antibodies  >1 publications with TRIP10 and Lung Neoplasms

Organs/Tissues associated with anti-TRIP10 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with TRIP10 and Blood
 Thyroid Antibodies  >6 publications with TRIP10 and Thyroid
 Brain Antibodies  >5 publications with TRIP10 and Brain
 Muscle Antibodies  >5 publications with TRIP10 and Muscle
 Kidney Antibodies  >4 publications with TRIP10 and Kidney
 Nerve Antibodies  >3 publications with TRIP10 and Nerve
 Heart Antibodies  >2 publications with TRIP10 and Heart
 Liver Antibodies  >2 publications with TRIP10 and Liver
 Lung Antibodies  >2 publications with TRIP10 and Lung
 Skin Antibodies  >1 publications with TRIP10 and Skin
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