HSV-2 gD Recombinant Protein – Cat# MBS553145

Herpes Simplex Virus-2 Gd (HSV-2 gD) Recombinant Protein

Name: HSV-2 gD Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS553145
Price: 995 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553145

Recombinant HSV-2 gD encodes the immunodominant sequences of the human Herpesvirus Glycoprotein D. This molecule has a calculated mass of approximately 14 kDa. Recombinant HSV2 gD contains an N terminal GST purification tag and migrates as an approximately 43… More details

$995 / 0.5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Herpes Simplex Virus-2 gD (HSV-2 gD), Recombinant Protein

Full Product Name

Recombinant Herpes Simplex Virus-2 gD

Product Gene Name

HSV-2 gD recombinant protein

Product Synonym Names

Herpes Simplex Virus-2 gD Recombinant ; hsv-2; hsv2; herpes simplex; hhv

Host

E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)

Form/Format

Sterile solution of 10mM Sodium Carbonate Bicarbonate pH 9.6, 0.1% SDS and 50% glycerol.

Purity/Purification

>95%, as determined by SDS-PAGE.

Concentration

8 mg/mL (lot specific)

Specificity

Immunoreactive with sera of infected HSV2 individuals.

Preparation and Storage

This protein can be stored in working aliquots at 2-8°C for one month, or at -20°C for 12 months without detectable loss of activity. Avoid repeated freeze/thaw cycles.

3D Structure

ModBase 3D Structure for P03172

Host Note

DNA sequence encoding immunodominant fragment of human Herpesvirus-2 Glycoprotein D was expressed in Escherichia Coli.

Endotoxin

Less than 0.1 EU/ug as determined by LAL method.

Product Categories/Family for HSV-2 gD recombinant protein

Viral Antigens

Other Notes

Small volumes of HSV-2 gD recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSV-2 gD purchase

MBS553145 is a recombinant protein targeting HSV-2 gD. Also known as Recombinant Herpes Simplex Virus-2 gD. Host: E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for HSV-2 gD. It may not necessarily be applicable to this product.

NCBI GI #

262527545

NCBI Accession #

P03172.2

UniProt Primary Accession #

P03172

UniProt Secondary Accession #

A7U8A6

NCBI Official Full Name

Envelope glycoprotein D

UniProt Protein Name

Envelope glycoprotein D

UniProt Gene Name

UniProt Synonym Gene Names

US6; gD

UniProt Entry Name

GD_HHV23

UniProt Comments for HSV-2 gD

Function: Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, PVRL1 and PVRL1. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL

By similarity.

Subunit structure: Homodimer

By similarity. Interacts with host receptor TNFRSF14. Interacts with host receptor PVRL1. Interacts with host receptor PVRL2. Interacts (via profusion domain) with gB; this interaction occurs in the absence of gH/gL. Interacts (via profusion domain) with gH/gL heterodimer; this interaction occurs in the absence of gB. Associates with the gB-gH/gL-gD complex. Interacts (via C-terminus) with UL11 tegument protein

By similarity. Ref.6 Ref.7

Subcellular location: Virion membrane; Single-pass type I membrane protein

By similarity. Note: During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs

By similarity.

Sequence similarities: Belongs to the herpesviridae glycoprotein D family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HSV-2 gD recombinant protein

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