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IGF-1r (CD221) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553175

Insulin-like growth factor 1 receptor (IGF-1R/CD221) is a membrane-associated tyrosine kinase receptor that plays an important role in cell growth, transformation, and protection of cells from a variety of apoptotic stimuli. IGF-1R (CD221) is a tetrameric… More details

$335 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IGF-1R (CD221), Recombinant Protein
Full Product Name
Human IGF-1R Recombinant (CD221)
Product Gene Name
Product Synonym Gene Name
IGF-R
Product Synonym Names
Human CD221 Recombinant (IGF1 Receptor) ; cd-221; CD221; IGFIR; JTK13; MGC142170; MGC142172; MGC18216; IGF1 Receptor; IGF-1R; IGF-IR
Host
HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant IGF-1 receptor is supplied as a 0.2 um filtered PBS solution, pH7.2.
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Preparation and Storage
Recombinant CD221, as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.

Avoid repeated freeze/thaw cycles.
Molecular Weight
15,940 Da
3D Structure
ModBase 3D Structure for P68069
Domain
Ig-like C2
Host Note
Optimized DNA sequence encoding extracellular domain of human IGF-1R (CD221) including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Recombinant human IGF-1R (CD221) is a monomer protein, due to glycosylation migrates as an approximately 320 kDa protein on SDS-PAGE.

Product Categories/Family for CD221 recombinant protein

Other Notes

Small volumes of CD221 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD221 purchase

MBS553175 is a recombinant protein targeting CD221. Also known as Human IGF-1R Recombinant (CD221). Host: HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for CD221. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Hemoglobin subunit gamma
UniProt Protein Name
Hemoglobin subunit gamma
UniProt Synonym Protein Names
Gamma-globin; Hemoglobin gamma chain
UniProt Gene Name
HBG
UniProt Entry Name
HBG_ATEPA

UniProt Comments for CD221

Function: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

Subunit structure: Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F).

Tissue specificity: Red blood cells.

Sequence similarities: Belongs to the globin family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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