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CD38 Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553320

CD38 is a broadly expressed type II transmembrane glycoprotein of ~45 kDa in its monomeric form. This consists of a short intracytoplasmic (IC) tail, a transmembrane domain and a major extracellular domain (ECD) formed by 256 of the 300 constituent amino… More details

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Product Overview

Online Datasheet in PDF
Product Name
CD38, Recombinant Protein
Full Product Name
Rat CD38 Recombinant
Product Gene Name
CD38 recombinant protein
Product Synonym Names
cd38; cd-38
Host
HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant Rat CD38 is supplied as a 0.2 um filtered PBS solution, pH7.2.
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Preparation and Storage
Recombinant Rat CD38, as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.

Avoid repeated freeze/thaw cycles.
Molecular Weight
34,436 Da
3D Structure
ModBase 3D Structure for Q64244
Domain
ADP ribosyl cyclase
Host Note
Optimized DNA sequence encoding extracellular domain of Rat CD38 including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Recombinant Rat CD38 is a monomer protein consisting of 269 amino acid residue subunits, due to glycosylation migrates as an approximately 45 kDa protein on SDS-PAGE.

Product Categories/Family for CD38 recombinant protein

Receptors CD

Other Notes

Small volumes of CD38 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD38 purchase

MBS553320 is a recombinant protein targeting CD38. Also known as Rat CD38 Recombinant. Host: HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for CD38. It may not necessarily be applicable to this product.

NCBI GI #
6978629
NCBI GeneID
25668
NCBI Accession #
NP_037259.1
UniProt Primary Accession #
Q64244
GenBank Nucleotide #
NM_013127.1
NCBI Official Full Name
ADP-ribosyl cyclase 1
UniProt Protein Name
ADP-ribosyl cyclase 1
UniProt Synonym Protein Names
CD38H; Cyclic ADP-ribose hydrolase 1
Protein Family
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
UniProt Gene Name
Cd38
UniProt Synonym Gene Names
cADPr hydrolase 1
UniProt Entry Name
CD38_RAT

NCBI Summary for CD38

ADP-ribosyl cyclase enzyme involved in regulation of cellular calcium levels [RGD, Feb 2006]

UniProt Comments for CD38

CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Cell cycle regulation; Lyase; Membrane protein, integral; Cell surface; Apoptosis; EC 3.2.2.6; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 2.4.99.20

Cellular Component: cell surface; membrane; intracellular membrane-bound organelle; plasma membrane; integral to membrane; nucleus

Molecular Function: transferase activity; phosphorus-oxygen lyase activity; hydrolase activity, acting on glycosyl bonds; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity

Biological Process: response to drug; response to retinoic acid; metabolic process; positive regulation of transcription, DNA-dependent; response to hormone stimulus; positive regulation of insulin secretion; female pregnancy; positive regulation of cell growth; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; B cell receptor signaling pathway; response to hydroperoxide; response to cytokine stimulus; response to hypoxia; positive regulation of vasoconstriction; positive regulation of B cell proliferation; negative regulation of bone resorption; negative regulation of transcription, DNA-dependent; response to progesterone stimulus; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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