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Hsp70B prime; HEAT shock protein 70 B' Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565156

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive… More details

$420 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
HSP70B' (Hsp70B prime; Heat shock protein 70 B'), Monoclonal Antibody
Full Product Name
HSP70B' monoclonal antibody (165f)
Product Gene Name
anti-Hsp70B prime; Heat shock protein 70 B' antibody
Product Synonym Names
HSP70B'
Clonality
Monoclonal
Isotype
IgG1
Clone Number
165f
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Purity/Purification
Protein G affinity purified.
Specificity
Recognizes human HSP70B'. Detects a band of ~70kDa by Western blot.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Molecular Weight
71,028 Da
OMIM
140555
3D Structure
ModBase 3D Structure for P17066
Immunogen
Synthetic peptide corresponding to the sequence near the C-terminus of human HSP70B'.

Product Categories/Family for anti-Hsp70B prime; Heat shock protein 70 B' antibody

Protein Synthesis & Folding
Applications Tested/Suitable for anti-Hsp70B prime; Heat shock protein 70 B' antibody
Western Blot (WB)
Application Notes for anti-Hsp70B prime; Heat shock protein 70 B' antibody
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~70kDa by Western blot.

Western Blot (WB) of anti-Hsp70B prime; Heat shock protein 70 B' antibody

Western blot analysis: Lane 1: MW marker, Lane 2: HSP70B' Recombinant Protein, Lane 3: HeLa Cell Lysate (Heat Shocked).
Mouse Anti-Hsp70B prime; HEAT shock protein 70 B' Monoclonal Antibody – Cat# MBS565156

Other Notes

Small volumes of anti-Hsp70B prime; Heat shock protein 70 B' antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hsp70B prime; Heat shock protein 70 B' purchase

MBS565156 is an antibody targeting Hsp70B prime; Heat shock protein 70 B'. Also known as HSP70B' monoclonal antibody (165f). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Hsp70B prime; Heat shock protein 70 B'. It may not necessarily be applicable to this product.

NCBI GI #
34978357
NCBI GeneID
3310
NCBI Accession #
P17066.2
UniProt Primary Accession #
P17066
UniProt Secondary Accession #
Q1HBA8; Q8IYK7; Q9BT95
UniProt Related Accession #
P17066
NCBI Official Full Name
Heat shock 70 kDa protein 6
NCBI Official Synonym Full Names
heat shock protein family A (Hsp70) member 6
NCBI Official Symbol
HSPA6
NCBI Official Synonym Symbols
HSP70B'
UniProt Protein Name
Heat shock 70 kDa protein 6
UniProt Synonym Protein Names
Heat shock 70 kDa protein B'
UniProt Gene Name
HSPA6
UniProt Synonym Gene Names
HSP70B'
UniProt Entry Name
HSP76_HUMAN
NCBI Protein Information
heat shock 70 kDa protein 6

UniProt Comments for Hsp70B prime; Heat shock protein 70 B'

HSPA6: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Belongs to the heat shock protein 70 family.

Protein type: Heat shock protein

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: centriole; cytoplasm; cytosol; signalosome

Molecular Function: ATP binding; ATPase activity, coupled; enzyme binding; heat shock protein binding; protein binding; unfolded protein binding

Biological Process: protein refolding; response to unfolded protein
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Research Articles on Hsp70B prime; Heat shock protein 70 B'

1. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Hsp70B prime; Heat shock protein 70 B' antibody

 Reference Product  PubMed Publications
 DNAJB1 antibody  >4 publications with Hsp70B prime; Heat shock protein 70 B' and DNAJB1
 HSP90AA1 antibody  >2 publications with Hsp70B prime; Heat shock protein 70 B' and HSP90AA1
 DNAJB6 antibody  >1 publications with Hsp70B prime; Heat shock protein 70 B' and DNAJB6
 HSP90AB1 antibody  >1 publications with Hsp70B prime; Heat shock protein 70 B' and HSP90AB1

Pathways associated with anti-Hsp70B prime; Heat shock protein 70 B' antibody

 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram

Diseases associated with anti-Hsp70B prime; Heat shock protein 70 B' antibody

 Disease Name  Pubmed Publications
 Melanoma Antibodies  >4 publications with Hsp70B prime; Heat shock protein 70 B' and Melanoma
 Inflammation Antibodies  >4 publications with Hsp70B prime; Heat shock protein 70 B' and Inflammation
 Brain Diseases Antibodies  >4 publications with Hsp70B prime; Heat shock protein 70 B' and Brain Diseases
 Cardiovascular Diseases Antibodies  >3 publications with Hsp70B prime; Heat shock protein 70 B' and Cardiovascular Diseases
 Necrosis Antibodies  >3 publications with Hsp70B prime; Heat shock protein 70 B' and Necrosis
 Nervous System Diseases Antibodies  >2 publications with Hsp70B prime; Heat shock protein 70 B' and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >2 publications with Hsp70B prime; Heat shock protein 70 B' and Neoplasms, Experimental
 Eye Diseases Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Eye Diseases
 Disease Models, Animal Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Disease Models, Animal
 Dermatitis, Allergic Contact Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Dermatitis, Allergic Contact

Organs/Tissues associated with anti-Hsp70B prime; Heat shock protein 70 B' antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >5 publications with Hsp70B prime; Heat shock protein 70 B' and Skin
 Blood Antibodies  >5 publications with Hsp70B prime; Heat shock protein 70 B' and Blood
 Brain Antibodies  >4 publications with Hsp70B prime; Heat shock protein 70 B' and Brain
 Muscle Antibodies  >2 publications with Hsp70B prime; Heat shock protein 70 B' and Muscle
 Eye Antibodies  >2 publications with Hsp70B prime; Heat shock protein 70 B' and Eye
 Connective Tissue Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Connective Tissue
 Placenta Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Placenta
 Pancreas Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Pancreas
 Prostate Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Prostate
 Bone Antibodies  >1 publications with Hsp70B prime; Heat shock protein 70 B' and Bone
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