Rabbit Anti-HEAT shock protein 40 Polyclonal Antibody – Cat# MBS565309

Immunohistochemistry analysis of human placenta tissue stained with HSP40/Hdj1, pAb at 10µg/ml.

HEAT shock protein 40 Antibody – Rabbit Polyclonal

Name: HEAT shock protein 40 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS565309
Price: 330 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565309

Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E Coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40… More details

$330 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HSP40/Hdj1 (Heat shock protein 40), Polyclonal Antibody

Full Product Name

HSP40/Hdj1 polyclonal antibody

Product Gene Name

anti-Heat shock protein 40 antibody

Product Synonym Names

HSP40/Hdj1

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Beluga, Bovine, Chicken, Dog, Fish, Guinea pig, Hamster, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Xenopus

Form/Format

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Purity/Purification

Protein A affinity purified.

Specificity

Recognizes human, mouse, rat, bovine, beluga, dog, chicken, fish, guinea pig, hamster, mouse, monkey, mussel, pig, rabbit, sheep, scallop and Xenopus HSP40 (Hdj1). Detects a band of ~40kDa by Western blot.

Preparation and Storage

Long term storage: -20 degree C
Avoid freeze/thaw cycles.

Molecular Weight

27,016 Da

OMIM

604572

3D Structure

ModBase 3D Structure for P25685

Immunogen

Recombinant human Hsp40.

Product Categories/Family for anti-Heat shock protein 40 antibody

Protein Synthesis & Folding

Applications Tested/Suitable for anti-Heat shock protein 40 antibody

Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)

Application Notes for anti-Heat shock protein 40 antibody

Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~40kDa by Western blot.

Other Notes

Small volumes of anti-Heat shock protein 40 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Heat shock protein 40 purchase

MBS565309 is an antibody targeting Heat shock protein 40. Also known as HSP40/Hdj1 polyclonal antibody. Reactive in Human, Mouse, Rat, Beluga, Bovine, Chicken, Dog, Fish, Guinea pig, Hamster, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Xenopus. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Heat shock protein 40. It may not necessarily be applicable to this product.

NCBI GI #

1706473

NCBI GeneID

3337

NCBI Accession #

P25685.4

UniProt Primary Accession #

P25685

UniProt Secondary Accession #

B4DX52

UniProt Related Accession #

P25685

NCBI Official Full Name

DnaJ homolog subfamily B member 1

NCBI Official Synonym Full Names

DnaJ heat shock protein family (Hsp40) member B1

NCBI Official Symbol

DNAJB1

NCBI Official Synonym Symbols

Hdj1; Sis1; HSPF1; Hsp40; RSPH16B

UniProt Protein Name

DnaJ homolog subfamily B member 1

UniProt Synonym Protein Names

DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1

UniProt Gene Name

DNAJB1

UniProt Synonym Gene Names

DNAJ1; HDJ1; HSPF1; HSP40; Heat shock protein 40; hDj-1

UniProt Entry Name

DNJB1_HUMAN

NCBI Protein Information

dnaJ homolog subfamily B member 1

NCBI Summary for Heat shock protein 40

This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

UniProt Comments for Heat shock protein 40

Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.

Research Articles on Heat shock protein 40

1. siRNA experiments confirmed that a reduction in Hsp27 or Hsp40 rescued CFTR in the DeltaF508 mutant, but the rescue was not additive or synergistic with C4 + 18 treatment, indicating these correctors shared a common pathway for rescue

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Heat shock protein 40 antibody

Reference Product	PubMed Publications
HSPA1A antibody	>24 publications with Heat shock protein 40 and HSPA1A
HSPA8 antibody	>23 publications with Heat shock protein 40 and HSPA8
HSF1 antibody	>10 publications with Heat shock protein 40 and HSF1
HSPH1 antibody	>8 publications with Heat shock protein 40 and HSPH1
HSPA6 antibody	>4 publications with Heat shock protein 40 and HSPA6
HSPA2 antibody	>3 publications with Heat shock protein 40 and HSPA2
HSP90AA1 antibody	>3 publications with Heat shock protein 40 and HSP90AA1
HSP90AB1 antibody	>1 publications with Heat shock protein 40 and HSP90AB1
HSPA4 antibody	>1 publications with Heat shock protein 40 and HSPA4

Pathways associated with anti-Heat shock protein 40 antibody

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Cellular Responses To Stress Pathway antibodies	Cellular Responses To Stress Pathway Diagram
HSF1-dependent Transactivation Pathway antibodies	HSF1-dependent Transactivation Pathway Diagram
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MAPK6/MAPK4 Signaling Pathway antibodies	MAPK6/MAPK4 Signaling Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with anti-Heat shock protein 40 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>17 publications with Heat shock protein 40 and Nervous System Diseases
Carcinoma, Hepatocellular Antibodies	>11 publications with Heat shock protein 40 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>10 publications with Heat shock protein 40 and Liver Diseases
Disease Models, Animal Antibodies	>8 publications with Heat shock protein 40 and Disease Models, Animal
Liver Neoplasms Antibodies	>8 publications with Heat shock protein 40 and Liver Neoplasms
Inflammation Antibodies	>8 publications with Heat shock protein 40 and Inflammation
Lung Diseases Antibodies	>7 publications with Heat shock protein 40 and Lung Diseases
Cardiovascular Diseases Antibodies	>4 publications with Heat shock protein 40 and Cardiovascular Diseases
Fibrosis Antibodies	>4 publications with Heat shock protein 40 and Fibrosis
Chromosome Aberrations Antibodies	>3 publications with Heat shock protein 40 and Chromosome Aberrations

Organs/Tissues associated with anti-Heat shock protein 40 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>23 publications with Heat shock protein 40 and Brain
Liver Antibodies	>18 publications with Heat shock protein 40 and Liver
Nerve Antibodies	>16 publications with Heat shock protein 40 and Nerve
Blood Antibodies	>15 publications with Heat shock protein 40 and Blood
Lung Antibodies	>6 publications with Heat shock protein 40 and Lung
Heart Antibodies	>5 publications with Heat shock protein 40 and Heart
Testis Antibodies	>5 publications with Heat shock protein 40 and Testis
Eye Antibodies	>4 publications with Heat shock protein 40 and Eye
Muscle Antibodies	>4 publications with Heat shock protein 40 and Muscle
Vascular Antibodies	>4 publications with Heat shock protein 40 and Vascular