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CCP110 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7044697

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545… More details

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Product Overview

Online Datasheet in PDF
Product Name
CCP110, Polyclonal Antibody
Full Product Name
CCP110 Antibody
Product Gene Name
Product Synonym Names
Centriolar coiled-coil protein of 110 kDa; Centrosomal protein of 110 kDa; CP110; Cep110; CCP110; CEP110; CP110; KIAA0419
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
111,224 Da
OMIM
609544
3D Structure
ModBase 3D Structure for O43303
Species
Human
Immunogen
Recombinant human Centriolar coiled-coil protein of 110 kDa protein (N-280AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-136629 / sc-136630
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CCP110 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-CCP110 antibody

Western blot
All lanes: CCP110 antibody at 4.6ug/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 114,112 kDa
Observed band size: 113 kDa
Rabbit Anti-CCP110 Polyclonal Antibody – Cat# MBS7044697

Immunohistochemistry (IHC) of anti-CCP110 antibody

Immunohistochemistry of paraffin-embedded human testis tissue using MBS7044697 at dilution 1:100
Rabbit Anti-CCP110 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7044697

Immunohistochemistry (IHC) of anti-CCP110 antibody

Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7044697 at dilution 1:100
Rabbit Anti-CCP110 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7044697

Other Notes

Small volumes of anti-CCP110 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCP110 purchase

MBS7044697 is an antibody targeting CCP110. Also known as CCP110 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCP110. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centriolar coiled-coil protein of 110 kDa isoform 1
NCBI Official Synonym Full Names
centriolar coiled-coil protein 110
NCBI Official Symbol
CCP110
NCBI Official Synonym Symbols
CP110; Cep110
UniProt Protein Name
Centriolar coiled-coil protein of 110 kDa
UniProt Synonym Protein Names
Centrosomal protein of 110 kDa; CP110; Cep110
UniProt Gene Name
CCP110
UniProt Synonym Gene Names
CEP110; CP110; KIAA0419; CP110; Cep110
UniProt Entry Name
CP110_HUMAN
NCBI Protein Information
centriolar coiled-coil protein of 110 kDa

UniProt Comments for CCP110

CP110: Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 16p12.3

Cellular Component: centriole; centrosome; cytosol; protein complex

Molecular Function: protein binding

Biological Process: basal body organization and biogenesis; centriole replication; centrosome duplication; G2/M transition of mitotic cell cycle; positive regulation of flagellum biogenesis; regulation of cytokinesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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