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UGGT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565311

UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to… More details

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Product Overview

Product Name
UGGT (Uggt1), Polyclonal Antibody
Full Product Name
UGGT polyclonal antibody
Product Gene Name
anti-Uggt1 antibody
Product Synonym Names
UGGT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Liquid. Whole rabbit serum.
Specificity
Recognizes mouse and rat UGGT. Detects a band of ~170kDa by Western blot.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Molecular Weight
176,431 Da
3D Structure
ModBase 3D Structure for Q9JLA3
Immunogen
Synthetic peptide corresponding to a portion of rat UGGT.

Product Categories/Family for anti-Uggt1 antibody

Metabolism
Applications Tested/Suitable for anti-Uggt1 antibody
Western Blot (WB)
Application Notes for anti-Uggt1 antibody
Western Blot (1:100 colorimetric, 1:500 ECL)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~170kDa by Western blot.

Western Blot (WB) of anti-Uggt1 antibody

Western blot analysis of rat brain tissue extract, probed with UGGT, pAb.
Rabbit Anti-UGGT1 Polyclonal Antibody – Cat# MBS565311

Other Notes

Small volumes of anti-Uggt1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Uggt1 purchase

MBS565311 is an antibody targeting Uggt1. Also known as UGGT polyclonal antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Uggt1. It may not necessarily be applicable to this product.

NCBI GI #
224471866
NCBI GeneID
171129
NCBI Accession #
Q9JLA3.2
UniProt Primary Accession #
Q9JLA3
UniProt Related Accession #
Q9JLA3
NCBI Official Full Name
UDP-glucose:glycoprotein glucosyltransferase 1
NCBI Official Synonym Full Names
UDP-glucose glycoprotein glucosyltransferase 1
NCBI Official Symbol
Uggt1
NCBI Official Synonym Symbols
UGT1; Uggt; rUGT1; Ugcgl1
UniProt Protein Name
UDP-glucose:glycoprotein glucosyltransferase 1
UniProt Synonym Protein Names
UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1
Protein Family
UDP-glucose:glycoprotein glucosyltransferase
UniProt Gene Name
Uggt1
UniProt Synonym Gene Names
; UGT1; rUGT1
UniProt Entry Name
UGGG1_RAT
NCBI Protein Information
UDP-glucose:glycoprotein glucosyltransferase 1

NCBI Summary for Uggt1

enzyme that catalyzes the addition of a glucose residue from UDP-glucose to an N -linked Man(9)GlcNAc(2)oligosaccharide [RGD, Feb 2006]

UniProt Comments for Uggt1

UGCGL1: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. Belongs to the glycosyltransferase 8 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.1.-

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; ER-Golgi intermediate compartment

Molecular Function: protein binding; UDP-glucose:glycoprotein glucosyltransferase activity; unfolded protein binding

Biological Process: 'de novo' posttranslational protein folding; protein amino acid glycosylation; protein folding
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Research Articles on Uggt1

1. UGGT recognizes the hydrophobic region of client glycoproteins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Uggt1 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Calnexin/calreticulin Cycle Pathway antibodies  Calnexin/calreticulin Cycle Pathway Diagram
 ER Quality Control Compartment (ERQC) Pathway antibodies  ER Quality Control Compartment (ERQC) Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-glycan Trimming In The ER And Calnexin/Calreticulin Cycle Pathway antibodies  N-glycan Trimming In The ER And Calnexin/Calreticulin Cycle Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with anti-Uggt1 antibody

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >1 publications with Uggt1 and Lung Diseases
 Liver Diseases Antibodies  >1 publications with Uggt1 and Liver Diseases
 Inflammation Antibodies  >1 publications with Uggt1 and Inflammation

Organs/Tissues associated with anti-Uggt1 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >1 publications with Uggt1 and Pancreas
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