Rabbit Anti-PHE-MET-ARG-PHE-amide Polyclonal Antibody – Cat# MBS565342

PHE-MET-ARG-PHE-amide Antibody – Rabbit Polyclonal

Name: PHE-MET-ARG-PHE-amide Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS565342
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565342

MBS565342 is an antibody targeting Phe-Met-Arg-Phe-amide. Also known as FMRFamide polyclonal antibody. Reactive in Species Independent. Host: Rabbit. More details

$285 / 0.025 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FMRFamide (Phe-Met-Arg-Phe-amide), Polyclonal Antibody

Full Product Name

FMRFamide polyclonal antibody

Product Gene Name

anti-Phe-Met-Arg-Phe-amide antibody

Product Synonym Names

Phe-Met-Arg-Phe-amide

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Species Independent

Form/Format

Liquid. Neat serum containing 0.1% sodium azide.

Specificity

Recognizes FMRF in multiple species including human.

Preparation and Storage

Long term storage: -20 degree C.
Shipping: Ships on Blue Ice.

OMIM

604643

3D Structure

ModBase 3D Structure for O15130

Immunogen

Synthetic FMRF-amide (Phe-Met-Arg-Phe-amide).

Host Note

Whole rabbit serum.

Product Categories/Family for anti-Phe-Met-Arg-Phe-amide antibody

Cell Signaling

Applications Tested/Suitable for anti-Phe-Met-Arg-Phe-amide antibody

Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-Phe-Met-Arg-Phe-amide antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Phe-Met-Arg-Phe-amide. It may not necessarily be applicable to this product.

NCBI GI #

8134595

NCBI GeneID

8620

NCBI Accession #

O15130.1

UniProt Primary Accession #

O15130

UniProt Secondary Accession #

Q3SXL4

UniProt Related Accession #

O15130

NCBI Official Full Name

Pro-FMRFamide-related neuropeptide FF

NCBI Official Synonym Full Names

neuropeptide FF-amide peptide precursor

NCBI Official Symbol

NPFF

NCBI Official Synonym Symbols

FMRFAL

UniProt Protein Name

Pro-FMRFamide-related neuropeptide FF

UniProt Synonym Protein Names

FMRFamide-related peptides

Protein Family

FMRFamide

UniProt Gene Name

NPFF

UniProt Synonym Gene Names

NPSF; NPFF; NPAF

UniProt Entry Name

NPFF_HUMAN

NCBI Protein Information

pro-FMRFamide-related neuropeptide FF

NCBI Summary for Phe-Met-Arg-Phe-amide

This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

UniProt Comments for Phe-Met-Arg-Phe-amide

NPFF: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. Belongs to the FARP (FMRFamide related peptide) family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytosol; dendrite; extracellular region; extracellular space; nerve terminal; perikaryon; vesicle

Molecular Function: G-protein-coupled receptor binding; neuropeptide hormone activity; receptor binding

Biological Process: acute inflammatory response to antigenic stimulus; elevation of cytosolic calcium ion concentration; maternal process involved in pregnancy; negative regulation of appetite; negative regulation of heart rate; negative regulation of insulin secretion; neuropeptide signaling pathway; positive regulation of blood pressure; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to drug; response to morphine; spinal cord development; synaptic transmission; vasopressin secretion

Research Articles on Phe-Met-Arg-Phe-amide

1. reduction of NPFF release within the dorsal motor nucleus and ambiguus nucleus could serve as a possible cause of the impairment of cardiac vagal control in hypertensive patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Phe-Met-Arg-Phe-amide antibody

Reference Product	PubMed Publications
QRFP antibody	>9 publications with Phe-Met-Arg-Phe-amide and QRFP
NPFFR2 antibody	>6 publications with Phe-Met-Arg-Phe-amide and NPFFR2
QRFPR antibody	>2 publications with Phe-Met-Arg-Phe-amide and QRFPR
NPFFR1 antibody	>2 publications with Phe-Met-Arg-Phe-amide and NPFFR1
KISS1R antibody	>1 publications with Phe-Met-Arg-Phe-amide and KISS1R

Pathways associated with anti-Phe-Met-Arg-Phe-amide antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway antibodies	Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with anti-Phe-Met-Arg-Phe-amide antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>16 publications with Phe-Met-Arg-Phe-amide and Inflammation
Vascular Diseases Antibodies	>7 publications with Phe-Met-Arg-Phe-amide and Vascular Diseases
Hypertension Antibodies	>6 publications with Phe-Met-Arg-Phe-amide and Hypertension
Hemorrhage Antibodies	>3 publications with Phe-Met-Arg-Phe-amide and Hemorrhage
Kidney Diseases Antibodies	>1 publications with Phe-Met-Arg-Phe-amide and Kidney Diseases
Edema Antibodies	>1 publications with Phe-Met-Arg-Phe-amide and Edema
Drug Hypersensitivity Antibodies	>1 publications with Phe-Met-Arg-Phe-amide and Drug Hypersensitivity

Organs/Tissues associated with anti-Phe-Met-Arg-Phe-amide antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>165 publications with Phe-Met-Arg-Phe-amide and Brain
Heart Antibodies	>15 publications with Phe-Met-Arg-Phe-amide and Heart
Intestine Antibodies	>6 publications with Phe-Met-Arg-Phe-amide and Intestine
Kidney Antibodies	>5 publications with Phe-Met-Arg-Phe-amide and Kidney
Pancreas Antibodies	>3 publications with Phe-Met-Arg-Phe-amide and Pancreas
Eye Antibodies	>2 publications with Phe-Met-Arg-Phe-amide and Eye
Epididymis Antibodies	>1 publications with Phe-Met-Arg-Phe-amide and Epididymis
Uncharacterized Tissue Antibodies	>1 publications with Phe-Met-Arg-Phe-amide and Uncharacterized Tissue