GM-CSF Recombinant Protein

Name: GM-CSF Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS567253
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS567253

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GM-CSF, Recombinant Protein

Full Product Name

GM-CSF (mouse), (recombinant)

Product Gene Name

GM-CSF recombinant protein

Host

E Coli

Form/Format

Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM acetic acid

Purity/Purification

>=95% (SDS-PAGE)

Preparation and Storage

For long term storage, store at -80 degree C
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80 degree C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution

Molecular Weight

16,091 Da

3D Structure

ModBase 3D Structure for P01587

Amino Acids

Contains 125 amino acids

Endotoxin

<=1EU/ug protein (LAL test)

Reconstitution

Reconstitute in sterile water at 0.1mg/mL

Product Categories/Family for GM-CSF recombinant protein

Cellular Analysis; Cell Growth & Development

Other Notes

Small volumes of GM-CSF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GM-CSF purchase

MBS567253 is a recombinant protein targeting GM-CSF. Also known as GM-CSF (mouse), (recombinant). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GM-CSF. It may not necessarily be applicable to this product.

NCBI GI #

110625658

NCBI GeneID

12981

NCBI Accession #

NP_034099.2

UniProt Primary Accession #

P01587

UniProt Related Accession #

P01587

GenBank Nucleotide #

NM_009969.4

NCBI Official Full Name

granulocyte-macrophage colony-stimulating factor

NCBI Official Synonym Full Names

colony stimulating factor 2 (granulocyte-macrophage)

NCBI Official Symbol

Csf2

NCBI Official Synonym Symbols

Csfgm; GMCSF; Gm-CSf; MGI-IGM

UniProt Protein Name

Granulocyte-macrophage colony-stimulating factor

UniProt Synonym Protein Names

Colony-stimulating factor; CSF

Protein Family

Granulocyte colony-stimulating factor receptor

UniProt Gene Name

Csf2

UniProt Synonym Gene Names

Csfgm; GM-CSF; CSF

UniProt Entry Name

CSF2_MOUSE

NCBI Protein Information

granulocyte-macrophage colony-stimulating factor; CSF; granulocyte-macrophage colony stimulating factor 2; put. GM-CSF

UniProt Comments for GM-CSF

GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity

Biological Process: negative regulation of cytolysis; epithelial fluid transport; embryonic placenta development; macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of gene expression; positive regulation of interleukin-23 production; positive regulation of cell proliferation; myeloid dendritic cell differentiation; immune response; positive regulation of DNA replication; regulation of cell proliferation

Research Articles on GM-CSF

1. Expression of PPAR-gamma in fetal lung monocytes was dependent on the cytokine GM-CSF. Therefore, GM-CSF has a lung-specific role in the perinatal development of alveolar macrophages through the induction of PPAR-gamma in fetal monocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GM-CSF recombinant protein

Products by Pathway	Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
G Beta:gamma Signalling Through PI3Kgamma Pathway antibodies	G Beta:gamma Signalling Through PI3Kgamma Pathway Diagram
G-protein Beta:gamma Signalling Pathway antibodies	G-protein Beta:gamma Signalling Pathway Diagram

Diseases associated with GM-CSF recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>41 publications with GM-CSF and Inflammation
Necrosis Antibodies	>26 publications with GM-CSF and Necrosis
Lung Diseases Antibodies	>9 publications with GM-CSF and Lung Diseases
Breast Neoplasms Antibodies	>7 publications with GM-CSF and Breast Neoplasms
Fibrosis Antibodies	>4 publications with GM-CSF and Fibrosis
Neoplasms, Experimental Antibodies	>4 publications with GM-CSF and Neoplasms, Experimental
Carcinoma Antibodies	>3 publications with GM-CSF and Carcinoma
Leukemia, Myeloid, Acute Antibodies	>3 publications with GM-CSF and Leukemia, Myeloid, Acute
Arthritis, Rheumatoid Antibodies	>3 publications with GM-CSF and Arthritis, Rheumatoid
Lung Neoplasms Antibodies	>3 publications with GM-CSF and Lung Neoplasms

Organs/Tissues associated with GM-CSF recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>12 publications with GM-CSF and Lung