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MD2-IN-1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750093

MBS5750093 is an inhibitor targeting MD2-IN-1. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MD2-IN-1, Inhibitor
Full Product Name
MD2-IN-1
Product Gene Name
MD2-IN-1, inhibitor
Form/Format
POWDER
Purity/Purification
99.4%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
358.39
CAS
111797-22-9
Formula
C20H22O6
Pathways
Immunology/Inflammation
Target
rhMD2
Smiles
COc1ccc(cc1OC)C(=O)\C=C\c1cc(OC)c(OC)c(OC)c1
Receptor
Myeloid differentiation protein 2  (MD2)
Bioactivity
MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 ?muM for the recombinant human MD2 (rhMD2).
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product References and Citations for MD2-IN-1, inhibitor

1. Zhang Y, et al. Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury. Sci Rep. 2016 Apr 27; 6:25130.

Other Notes

Small volumes of MD2-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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