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AS1517499 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750582

MBS5750582 is an inhibitor targeting AS1517499. AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AS1517499, Inhibitor
Full Product Name
AS1517499
Product Gene Name
AS1517499, inhibitor
Product Synonym Names
JAK/STAT Signaling; Stem Cell/Wnt
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
397.86
CAS Number
919486-40-1
Formula
C20H20ClN5O2
Smiles
NC(=O)c1cnc(NCCc2ccc(O)c(Cl)c2)nc1NCc1ccccc1
Solubility
DMSO: >=35 mg/mL
Pathways
JAK; STAT Signaling; Stem Cells
Receptor
STAT6
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for AS1517499, inhibitor

Inflammation/Immunology

Chemical Structure of AS1517499, inhibitor

AS1517499 Inhibitor – Cat# MBS5750582

Product References and Citations for AS1517499, inhibitor

1. Nagashima S, et al. Synthesis and evaluation of 2-{[2-(4-hydroxyphenyl)-ethyl]amino}pyrimidine-5-carboxamide derivatives as novel STAT6 inhibitors. Bioorg Med Chem. 2007 Jan 15; 15(2):1044-55.

Other Notes

Small volumes of AS1517499, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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