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JNJ-10229570 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751864

JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JNJ-10229570, Inhibitor
Full Product Name
JNJ-10229570
Product Gene Name
Product Synonym Names
JNJ10229570; UNII-N9IX402L35; JNJ 10229570
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
389.47
Formula
C22H19N3O2S
CAS
524923-88-4
Smiles
COc1ccccc1-c1nc(=Nc2ccccc2)sn1-c1ccccc1OC
Receptor (IC50)
human MC1R: 270nM
human MC5R: 200nM
Solubility
DMSO: 62.5mg/mL (160.47mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for JNJ-10229570, inhibitor

Product References and Citations for JNJ-10229570, inhibitor

1. Eisinger M, et al. A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids. J Dermatol Sci. 2011 Jul;63 (1):23-32.

Other Notes

Small volumes of JNJ-10229570, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JNJ-10229570 purchase

MBS5751864 is an inhibitor targeting JNJ-10229570.
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