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N-Formyl-Met-Leu-Phe Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752310

N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
N-Formyl-Met-Leu-Phe, Inhibitor
Full Product Name
N-Formyl-Met-Leu-Phe
Product Synonym Names
fMLP; N-Formyl-MLF
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
437.55
Formula
C21H31N3O5S
CAS
59880-97-6
Smiles
CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Receptor (IC50)
formyl peptide receptor (FPR)
Solubility
DMSO: 82.5mg/mL (188.55mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for N-Formyl-Met-Leu-Phe, inhibitor

Product References and Citations for N-Formyl-Met-Leu-Phe, inhibitor

1. Lad P M, Olson C V, Smiley P A. Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin.[J]. Proceedings of the National Academy of Sciences, 1985, 82 (3):869-873.
2. Shin M K, Jang Y H, Yoo H J, et al. N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow[J]. Journal of Biological Chemistry, 2011, 286 (19):17133-17143.

Other Notes

Small volumes of N-Formyl-Met-Leu-Phe, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for N-Formyl-Met-Leu-Phe purchase

MBS5752310 is an inhibitor targeting N-Formyl-Met-Leu-Phe.
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