GENZ-644282 Inhibitor

Name: GENZ-644282 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752393
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752393

Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Genz-644282, Inhibitor

Full Product Name

Genz-644282

Product Gene Name

Genz-644282, inhibitor

Product Synonym Names

Genz644282

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

407.42

Formula

C22H21N3O5

CAS

529488-28-6

Smiles

CNCCn1c2c(cnc3cc4OCOc4cc23)c2cc(OC)c(OC)cc2c1=O

Receptor (IC50)

Topoisomerase

Solubility

DMSO: 5mg/mL (12.27mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Genz-644282, inhibitor

Home; DNA Damage/DNA Repair; Topoisomerase

Product References and Citations for Genz-644282, inhibitor

. Kurtzberg L S, Roth S, Krumbholz R, et al. Genz-644282, a Novel Non-Camptothecin Topoisomerase I Inhibitor for Cancer Treatment[J]. Clinical Cancer Research, 2011, 17 (9):2777-2787.
2. Houghton P J, Lock R, Carol H, et al. Testing of the Topoisomerase 1 Inhibitor Genz644282 by the Pediatric Preclinical Testing Program[J]. Pediatric Blood & Cancer, 2012, 58 (2):200-209.

Other Notes

Small volumes of Genz-644282, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Genz-644282 purchase

MBS5752393 is an inhibitor targeting Genz-644282.