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AMG-510 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752473

AMG-510 is a potent KRAS G12C covalent inhibitor, treatment with AMG 510 led to the regression of KRASG12C tumours and improved the anti-tumour efficacy of chemotherapy and targeted agents. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMG-510, Inhibitor
Full Product Name
AMG-510
Product Gene Name
AMG-510, inhibitor
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
560.59
Formula
C30H30F2N6O3
Smiles
CC(C)c1nccc(C)c1-n1c2nc(c(F)cc2c(nc1=O)N1CCN(C[C@@H]1C)C(=O)C=C)-c1c(O)cccc1F
Receptor (IC50)
KRAS G12C
Solubility
DMSO: 50mg/mL (89.19mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AMG-510, inhibitor

Home; MAPK; Ras

Structure of AMG-510, inhibitor

AMG-510 Inhibitor – Cat# MBS5752473

Other Notes

Small volumes of AMG-510, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMG-510 purchase

MBS5752473 is an inhibitor targeting AMG-510.
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