NGI-1 Inhibitor

Name: NGI-1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752506
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752506

NGI-1 is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NGI-1, Inhibitor

Full Product Name

NGI-1

Product Gene Name

NGI-1, inhibitor

Product Synonym Names

ML414

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

394.51

Formula

C17H22N4O3S2

CAS

790702-57-7

Smiles

CN(C)S(=O)(=O)c1ccc(N2CCCC2)c(c1)C(=O)Nc1ncc(C)s1

Receptor (IC50)

oligosaccharyltransferase

Solubility

DMSO: 160mg/mL (405.57mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for NGI-1, inhibitor

Home; Others

Product References and Citations for NGI-1, inhibitor

1. Lopez-Sambrooks C, Shrimal S, Khodier C, et al. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells[J]. Nature Chemical Biology, 2016.
2. Lu H, Cherepanova N A, Gilmore R, et al. Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction[J]. The FASEB Journal, 2019.

Other Notes

Small volumes of NGI-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NGI-1 purchase

MBS5752506 is an inhibitor targeting NGI-1.