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(1S,2S,3R)-DT-061 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752590

(1S,2S,3R)-DT-061 is an enantiomer of DT-061 which is an orally bioavailable activator of PP2A. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
(1S,2S,3R)-DT-061, Inhibitor
Full Product Name
(1S,2S,3R)-DT-061
Product Gene Name
(1S,2S,3R)-DT-061, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
520.52
Solubility
DMSO: 125mg/mL (240.14mM) Need ultrasonic
Methanol: 25mg/mL (48.03mM) Need ultrasonic
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H23F3N2O5S
SMILES
O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@@H]2[C@@H](O)[C@H](N3C4=C(C=CC=C4)OC5=CC=CC=C35)CCC2)=O
CAS Number
1809427-20-0
Target & IC50
Others

Structure of (1S,2S,3R)-DT-061, inhibitor

(1S,2S,3R)-DT-061 Inhibitor – Cat# MBS5752590

Product References and Citations for (1S,2S,3R)-DT-061, inhibitor

Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.

Other Notes

Small volumes of (1S,2S,3R)-DT-061, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (1S,2S,3R)-DT-061 purchase

MBS5752590 is an inhibitor targeting (1S,2S,3R)-DT-061.
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