AZ82 Inhibitor

Name: AZ82 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752746
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752746

AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43nM; IC50: 300nM for KIFC1). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZ82, Inhibitor

Full Product Name

AZ82

Product Gene Name

AZ82, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

560.63

Solubility

DMSO: 125mg/mL (222.96mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C28H31F3N4O3S

SMILES

O=C(C1=CC(CCC)=C(C)S1)N[C@H](CC2=CC=C(C3=CC=CC(OC(F)(F)F)=C3)N=C2)C(N[C@H]4CNCC4)=O

CAS Number

1449578-65-7

Target & IC50

HSET/KIFC1: ic50 43nM (ki)

Product Categories/Family for AZ82, inhibitor

Cytoskeletal Signaling; Microtubule Associated

Product References and Citations for AZ82, inhibitor

Godinho SA, et al. Causes and consequences of centrosome abnormalities in cancer. Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650).
Godinho SA, et al. Causes and consequences of centrosome abnormalities in cancer. Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650).
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1. Wu J, et al. ACS Chem Biol. 2013 Oct 18;8(10):2201-8.
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1. Wu J, et al. ACS Chem Biol. 2013 Oct 18;8(10):2201-8.

Other Notes

Small volumes of AZ82, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ82 purchase

MBS5752746 is an inhibitor targeting AZ82.