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BM635 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752804

BM635 is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12uM against M. tuberculosis H37Rv). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BM635, Inhibitor
Full Product Name
BM635
Product Gene Name
BM635, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
392.51
Solubility
DMSO: 31mg/mL (78.98mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H29FN2O
SMILES
CC(C1=CC=C(C2=CC(CN3CCOCC3)=C(C)N2C4=CC=C(F)C=C4)C=C1)C
CAS Number
1493762-74-5
Target & IC50
M. tuberculosis H37Rv: ic50 0.12uM (MIC50)

Structure of BM635, inhibitor

BM635 Inhibitor – Cat# MBS5752804

Product References and Citations for BM635, inhibitor

Poce G, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2):e56980.
Poce G, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2):e56980.
Poce G, et al. Pharmaceutical salt of BM635 with improved bioavailability. Eur J Pharm Sci. 2017 Mar 1;99:17-23.
Poce G, et al. Pharmaceutical salt of BM635 with improved bioavailability. Eur J Pharm Sci. 2017 Mar 1;99:17-23.

Other Notes

Small volumes of BM635, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BM635 purchase

MBS5752804 is an inhibitor targeting BM635.
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