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BMS-191095 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752807

BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BMS-191095, Inhibitor
Full Product Name
BMS-191095
Product Gene Name
BMS-191095, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
408.88
Solubility
DMSO: 50mg/mL (122.29mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H21ClN4O2
SMILES
CC(O1)(C)[C@H](O)[C@@H](N(CC2=NC=CN2)C3=CC=C(Cl)C=C3)C4=C1C=CC(C#N)=C4
CAS Number
166095-21-2
Target & IC50
Others
In Vitro
In normal rats, BMS-191095-induced vasodilation was mediated by mitochondrial depolarization and calcium sparks generation in VSM and was reduced by inhibition of BKCa channels.

Structure of BMS-191095, inhibitor

BMS-191095 Inhibitor – Cat# MBS5752807

Product References and Citations for BMS-191095, inhibitor

Katakam PV, et al. Diversity of mitochondria-dependent dilator mechanisms in vascular smooth muscle of cerebral arteries from normal and insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H493-503.
Katakam PV, et al. Diversity of mitochondria-dependent dilator mechanisms in vascular smooth muscle of cerebral arteries from normal and insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H493-503.

Other Notes

Small volumes of BMS-191095, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-191095 purchase

MBS5752807 is an inhibitor targeting BMS-191095.
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