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IRAK4-IN-4 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753336

IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1nM.IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IRAK4-IN-4, Inhibitor
Full Product Name
IRAK4-IN-4
Product Gene Name
IRAK4-IN-4, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
340.37
Solubility
DMSO: 24mg/mL (70.51mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H16N2O2
SMILES
Cc1ccn2c(C(=O)C(=O)c3ccccc3)c(nc2c1)-c1ccccc1
CAS Number
1850276-58-2
Target & IC50
IRAK4: ic50 2.8nM
cGAS: ic50 2.1nM

Structure of IRAK4-IN-4, inhibitor

IRAK4-IN-4 Inhibitor – Cat# MBS5753336

Product References and Citations for IRAK4-IN-4, inhibitor

One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.

Other Notes

Small volumes of IRAK4-IN-4, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IRAK4-IN-4 purchase

MBS5753336 is an inhibitor targeting IRAK4-IN-4.
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