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LYS-SMCC-DM1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753443

MBS5753443 is an inhibitor targeting Lys-SMCC-DM1. DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Lys-SMCC-DM1, Inhibitor
Full Product Name
Lys-SMCC-DM1
Product Gene Name
Lys-SMCC-DM1, inhibitor
Product Synonym Names
Lys-Nepsilon-MCC-DM1
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
1103.71
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C53H75ClN6O15S
SMILES
C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCS[C@@H](CC4=O)C(N4C[C@@H]5CC[C@@H](C(NCCCC[C@H](N)C(O)=O)=O)CC5)=O)=O)=O)[C@H]([C@@H]([C@](OC6=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N6)O)C)O1
CAS Number
1281816-04-3
Target & IC50
Maytansinoids

Structure of Lys-SMCC-DM1, inhibitor

LYS-SMCC-DM1 Inhibitor – Cat# MBS5753443

Product References and Citations for Lys-SMCC-DM1, inhibitor

Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

Other Notes

Small volumes of Lys-SMCC-DM1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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