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MCL-1/BCL-2-IN-2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753465

MBS5753465 is an inhibitor targeting MCL-1/BCL-2-IN-2. MCL-1/BCL-2-IN-2 is a potent and selective Bcl-2 and Mcl-1 dual inhibitor. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCL-1/BCL-2-IN-2, Inhibitor
Full Product Name
MCL-1/BCL-2-IN-2
Product Gene Name
MCL-1/BCL-2-IN-2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
427.31
Solubility
DMSO: 5mg/mL (11.70mM) ultrasonic and warming and heat to 60 degree C
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H15BrN2O2S
SMILES
O=C1N(CCN)C(C2=CC=C(SC3=CC=C(Br)C=C3)C4=CC=CC1=C24)=O
CAS Number
2163793-44-8
Target & IC50
Others

Product References and Citations for MCL-1/BCL-2-IN-2, inhibitor

Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Other Notes

Small volumes of MCL-1/BCL-2-IN-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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