trans-Ned 19 Inhibitor

Name: trans-Ned 19 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753568
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753568

trans-Ned 19 is a NAADP antagonist and TPC blocker and inhibits the calcium signal in human umbilical vein endothelial cells and the rat aorta relaxation in response to low histamine concentrations. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

trans-Ned 19, Inhibitor

Full Product Name

trans-Ned 19

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

514.59

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C30H31FN4O3

SMILES

O=C([C@@H]1CC2=C([C@@H](C3=CC=C(OC)C(CN4CCN(C5=CC=CC=C5F)CC4)=C3)N1)NC6=C2C=CC=C6)O

CAS Number

1354235-96-3

Target & IC50

Ca2+

Product Categories/Family for trans-Ned 19, inhibitor

Membrane transporter/Ion channel; Calcium Channel

Product References and Citations for trans-Ned 19, inhibitor

Zharkich IL, et al. Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide. Izv Akad Nauk Ser Biol. 2016 Jul;(4):430-438.

Other Notes

Small volumes of trans-Ned 19, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for trans-Ned 19 purchase

MBS5753568 is an inhibitor targeting trans-Ned 19.