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PF-2771 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753679

MBS5753679 is an inhibitor targeting PF-2771. PF-2771 is an inhibitor of centromere protein E (CENP-E)(IC50 of 16.1nM). More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-2771, Inhibitor
Full Product Name
PF-2771
Product Gene Name
PF-2771, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
554.08
Solubility
DMSO: 32mg/mL (57.75mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C29H36ClN5O4
SMILES
ClC1=CC(C(N[C@@H](CC2=CC=C(C3=CN(C)C(C(C)=O)=N3)C=C2)CNC(CN(C)C)=O)=O)=CC=C1OC(C)C
Target & IC50
CENP-E: ic50 16.1nM

Product Categories/Family for PF-2771, inhibitor

Cytoskeletal Signaling; Kinesin

Structure of PF-2771, inhibitor

PF-2771 Inhibitor – Cat# MBS5753679

Product References and Citations for PF-2771, inhibitor

Kung PP, et al. Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer. Mol Cancer Ther. 2014 Aug;13(8):2104-15.
Kung PP, et al. Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer. Mol Cancer Ther. 2014 Aug;13(8):2104-15.

Other Notes

Small volumes of PF-2771, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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