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SNT-207707 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753934

SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8nM (binding) and 5nM (function) on the MC-4 receptor). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SNT-207707, Inhibitor
Full Product Name
SNT-207707
Product Gene Name
SNT-207707, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
550.18
Solubility
DMSO: 250mg/mL (454.40mM)
Methanol: 250mg/mL (454.40mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C32H44ClN5O
SMILES
O=C(C1=CN2C(C=C1)=NC(C3=CC=C(C#N)C=C3)=C2CCCN4CCCC4)N(CCC(C)C)CCC(C)C.Cl
CAS Number
1064662-40-3
Target & IC50
binding MC-4: ic50 8nM
function MC-4: ic50 5nM
In Vitro
food intake of the mice distinctly increased by SNT-207707(Single subcutaneous injection of 20mg/kg). Once daily oral administration of both compounds SNT207858 and SNT-207707 starting the day after tumor implantation significantly reduces the tumor induced weight loss.

Structure of SNT-207707, inhibitor

SNT-207707 Inhibitor – Cat# MBS5753934

Product References and Citations for SNT-207707, inhibitor

Weyermann P, et al. Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice. PLoS One. 2009;4(3):e4774.

Other Notes

Small volumes of SNT-207707, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNT-207707 purchase

MBS5753934 is an inhibitor targeting SNT-207707.
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